Prevalence of chronic renal insufficiency in diabetic type 2 diabetes patients based on the estimated glomerular filtration rate and relation with cardiovascular risk

Medicina clínica
Teresa Mur MartíAngels Jaén Manzanera

Abstract

The aim of this study was: to estimate the prevalence of chronic renal insufficiency (CRI) in diabetic type 2 (DM2) patients treated in Primary Care based on the estimated glomerular filtration rate (GFe); to determine associated factors with CRI, and to evaluate the relationship of GF rate and risk of cardiovascular disease. This was a descriptive cross-sectional study. We included 500 medical histories randomly selected in a total of 2,950 DM2 patients. We registered sociodemographic data, comorbidities, cardiovascular risk factors and laboratory data. CRI definition was based on GFe rate and classified according to the K/DOQI Clinical Practice Guidelines for Chronic Kidney Disease. The prevalence of CRI was 23.2%. There were 51.6% females and the mean age was 66.2 years; 70,4% had hypertension and 67% dyslipidemia. The presence of CRI was related with older age, females, smoking habit, plasma creatinine value, microalbuminuria, and history of hypertension, dyslipidemia and cardiovascular disease. After analysing the data according to the category of GF rate, only the significant relationship with smoking habit disappeared. Multivariate statistic analysis supports a relation with older age, female gender, dyslipidemia and hea...Continue Reading

References

Jun 24, 2003·Journal of the American Society of Nephrology : JASN·Steven J ChadbanRobert C Atkins
Jun 26, 2003·JAMA : the Journal of the American Medical Association·Holly J KramerChi-Yuan Hsu
Sep 24, 2004·The New England Journal of Medicine·Alan S GoChi-yuan Hsu
Jun 29, 2005·Circulation·Peter LibbyUNKNOWN National Institute of Diabetes and Digestive and Kidney Diseases Working Group on Cardiovascular Complications of Type 1 Dia
Dec 29, 2009·Medicina clínica·Pedro Luis de Pablos-VelascoUNKNOWN en representación del Grupo de Investigadores DIABIR

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