Prevalence of coagulation abnormalities associated with intrauterine fetal death

Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie
A D MaslowN E Oriol

Abstract

The purpose of this study was to determine factors associated with abnormal coagulation in the setting of intrauterine fetal death (IUFD). We reviewed the charts of 238 patients diagnosed with IUFD over ten years. Data included demographics, co-existing obstetric disease and coagulation studies. A coagulation score was assigned based on the platelet count, prothrombin time, activated partial thromboplastin time and plasma fibrinogen concentration. Approximately 90% of the study population had coagulation scores < 4. A score of > or = 4 was considered abnormal. Complete coagulation analysis was available in 183/238 patients (77%) within 24 hr of delivery. One hundred and sixty-four of these (89.6%) had a coagulation score, < 4 and 19 had a score > or = 4 (10.4%). No relationship between the coagulation score and age, parity, gestational age at delivery, and number of days the dead fetus remained in utero was found. A coagulation score > = or 4 was associated with the presence of a pregnancy-related disease (P < 0.05), notably abruption (P < 0.001) and uterine perforation (P < 0.05). Four patients without co-existing disease (3.2%), had a coagulation score > or = 4. In most pregnancies complicated by fetal demise, the fetus and p...Continue Reading

References

Jul 15, 1978·American Journal of Obstetrics and Gynecology·G Müller-BerghausI Mahn
Apr 1, 1979·American Journal of Obstetrics and Gynecology·H SchulmanG Randolph
Jan 1, 1977·Journal of Clinical Pathology·V FentonI Cavill
Jan 1, 1975·Acta Obstetricia Et Gynecologica Scandinavica·H Gjonnaess, M K Fagerhol
Jan 1, 1990·International Anesthesiology Clinics·W R Camann, G W Ostheimer
May 1, 1989·The Medical Clinics of North America·B E Finley
Mar 1, 1989·Obstetrical & Gynecological Survey·H J Landy, A B Weingold
Dec 1, 1985·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·U Megafu
Jun 1, 1985·Annals of Internal Medicine·A I Schafer
Jul 21, 1988·The New England Journal of Medicine·R F Burrows, J G Kelton
Feb 1, 1986·Chest·J HirshL Poller
Feb 1, 1986·Chest·M DunnF Hildner
May 1, 1986·Chest·J Hirsh, R D Hull
Sep 1, 1986·American Journal of Obstetrics and Gynecology·W F O'BrienG R Cohen
Jan 1, 1972·Acta Obstetricia Et Gynecologica Scandinavica·B Astedt
Jan 1, 1967·Acta Obstetricia Et Gynecologica Scandinavica·I M Nilsson, S Kullander
May 1, 1982·European Journal of Obstetrics, Gynecology, and Reproductive Biology·F K Beller, C Ebert
Jun 1, 1983·Obstetrics and Gynecology·J C Jarrett, W N Spellacy
Jul 6, 1995·The New England Journal of Medicine·UNKNOWN European Atrial Fibrillation Trial Study Group
Nov 25, 1993·The New England Journal of Medicine·M C AllenA E Dusman
Oct 1, 1956·Surgery, Gynecology & Obstetrics·R J IRETON, J C ULLERY
Nov 1, 1960·World-wide Abstracts of General Medicine·J V MEIGS
Sep 1, 1960·Clinical Obstetrics and Gynecology·H H WARE
Aug 1, 1964·American Journal of Obstetrics and Gynecology·L L PHILLIPST A KING
Nov 1, 1950·American Journal of Obstetrics and Gynecology·A E WEINERL K DIAMOND

❮ Previous
Next ❯

Citations

Aug 3, 2007·Journal of Gastroenterology·Kazushige KawaiJunichi Shindoh
Jan 26, 2012·Thrombosis and Haemostasis·Tiziana CotechiniCharles H Graham
Oct 30, 2004·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·F A SaadA M Abu-Saleh
Sep 8, 2010·International Journal of Obstetric Anesthesia·G Dubar, D Benhamou
Sep 6, 2015·Seminars in Perinatology·Nahida A Chakhtoura, Uma M Reddy
Oct 25, 2016·Contraception·Amber N Fontenot FerrissKristina Tocce
Jan 22, 2011·Obstetrics and Gynecology·Andrea G EdlowAlisa B Goldberg
Jul 22, 2015·Anesthesia and Analgesia·Mary DiMiceli-ZsigmondMichael G Richardson

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.

Related Papers

Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research
Yanfang GuoGraeme N Smith
American Journal of Obstetrics and Gynecology
A RebarberC J Lockwood
Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology
R BaggaV Suri
© 2021 Meta ULC. All rights reserved