Prevalence of erythromycin and clindamycin resistance among clinical isolates of the Streptococcus anginosus group in Germany

Journal of Medical Microbiology
Nadine AsmahM Arvand

Abstract

Members of the Streptococcus anginosus group (SAG) are frequently involved in pyogenic infections in humans. In the present study, the antimicrobial susceptibility of 141 clinical SAG isolates to six antimicrobial agents was analysed by agar dilution. All isolates were susceptible to penicillin, cefotaxime and vancomycin. However, 12.8 % displayed increased MIC values (0.12 mg l(-1)) for penicillin. Resistance to erythromycin was detected in eight (5.7 %) isolates. Characterization of the erythromycin-resistant isolates with the double-disc diffusion test revealed Macrolide-Lincosamide-Streptogramin(B) and M-type resistance in six and two isolates, respectively. The erythromycin-resistant isolates were further characterized by PCR for the resistance genes ermA, ermB and mefA. Resistance and intermediate resistance to ciprofloxacin were detected in two and six isolates, respectively. Molecular typing by PFGE revealed a high genetic heterogeneity among the SAG isolates and no evidence for a clonal relationship between the erythromycin-resistant isolates. Our data show that resistance to erythromycin, clindamycin and ciprofloxacin has emerged among SAG isolates in Germany. The implications of these findings for susceptibility test...Continue Reading

References

Dec 1, 1993·The Journal of Antimicrobial Chemotherapy·H SeppäläP Huovinen
Nov 1, 1996·Antimicrobial Agents and Chemotherapy·J SutcliffeL Wondrack
Feb 13, 1999·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·R PallaresF Gudiol
Aug 12, 1999·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·A LimiaM López-Brea
Oct 6, 2000·The Journal of Antimicrobial Chemotherapy·M ArvandJ Wagner
Jan 4, 2001·International Journal of Antimicrobial Agents·D M Livermore
Apr 17, 2001·Antimicrobial Agents and Chemotherapy·M TracyD M Musher
Apr 24, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J E ClaridgeS Dunbar
Dec 26, 2001·The Journal of Antimicrobial Chemotherapy·Ralf René ReinertRudolf Lütticken
Oct 5, 2002·Clinical Microbiology Reviews·Richard Facklam
Sep 16, 2003·The Journal of Antimicrobial Chemotherapy·Helena SeppäläPentti Huovinen
Jun 22, 2005·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·T E SchoeningM Arvand
Feb 3, 2006·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·K B LauplandD B Gregson
May 4, 2006·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·T M File
Jan 25, 2007·Journal of Medical Microbiology·Rashid M RashidJorge P Parada

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Citations

Apr 21, 2010·Antimicrobial Agents and Chemotherapy·Margot E GrinwisMichael G Surette
May 14, 2010·Journal of Clinical Microbiology·Christopher D SibleyMichael G Surette
Sep 24, 2010·Future Microbiology·Christopher D SibleyMichael G Surette
Apr 1, 2014·European Journal of Trauma and Emergency Surgery : Official Publication of the European Trauma Society·P MathurM C Misra
Jul 3, 2013·The Journal of Antimicrobial Chemotherapy·François GraveyVincent Cattoir
Nov 13, 2013·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Ralph K JunckerstorffRonan J Murray
Jun 22, 2016·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·T HalperinL Valinsky
Sep 30, 2016·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Jun HiraiHiroshige Mikamo
May 5, 2017·Open Forum Infectious Diseases·Ryan C MavesTodd C Villines

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