Prevalence of extraesophageal reflux in patients with symptoms of gastroesophageal reflux

Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
Riitta YlitaloElisabeth Lindgren

Abstract

To compare the prevalence of extraesophageal reflux (EER) in patients with heartburn, posterior laryngitis (PL), and in healthy controls. Study design and setting A retrospective and prospective study including a total of 101 subjects who underwent 24-hour dual-probe pH monitoring. 52% of the subjects with heartburn had EER. No significant differences were found between the PL and heartburn groups for any pharyngeal reflux parameters. However, supine pharyngeal reflux was significantly more prevalent in heartburn patients with GERD than in PL patients and healthy controls (P < 0.05). Significant positive correlation (P < 0.01) was found between the percentage of time pH <4 in the pharynx and in the distal esophagus. EER occurs in the majority of heartburn patients who are lacking laryngeal symptoms. Abnormal distal esophageal acid exposure makes the occurrence of EER more likely. EER appears to be a continuum without clear-cut differences between the groups.

References

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May 23, 2002·The Annals of Otology, Rhinology, and Laryngology·Riitta Ylitalo, Stig Ramel
Aug 6, 2002·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·James A KoufmanGary Y Shaw

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Citations

May 27, 2006·Current Opinion in Otolaryngology & Head and Neck Surgery·Marc Remacle, Georges Lawson
Sep 18, 2012·Otolaryngologic Clinics of North America·Michael Lupa, John M DelGaudio
Oct 8, 2005·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·R YlitaloS Hertegård
Feb 14, 2006·Journal of Voice : Official Journal of the Voice Foundation·Nadine P ConnorDiane M Bless
Jul 19, 2006·Acta Oto-laryngologica·Simonetta MoniniMaurizio Barbara
May 27, 2014·Acta Oto-laryngologica·Marek KrawczykMaciej Misiołek
Dec 27, 2012·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Joel E Richter
Feb 17, 2015·World Journal of Clinical Cases·Andrea CiorbaCarlo Vittorio Feo

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