Prevalence of gastric cancer precursors in gastroscopy-screened adults by family history of gastric cancer and of cancers other than gastric.

BMC Cancer
Rui WuQiang Zhan

Abstract

People are at a high risk of gastric cancer if their first-degree relatives suffered from atrophic gastritis (AG), intestinal metaplasia (IM), intraepithelial neoplasia (IEN), dysplasia (DYS), or gastric cancer (GC). This study was performed to analyse the association between FDR-GC and GC precursors. A cross-sectional study was performed to screen the prevalence of GC precursors from November 2016 to September 2019. A total of 1329 participants with FDR-GC, 193 participants with a family history of non-gastric cancer in FDRs (FDR-nGC), and 860 participants without a family history of cancer in FDRs (FDR-nC) were recruited in this study. The logistic regression model was used in this study. The prevalence of normal, Non-AG, AG/IM, IEN/DYS, and GC was 31.91, 44.21, 13.81, 8.73, and 1.34%, respectively. The prevalence of IEN/DYS was higher in people with FDR-GC and FDR-nGC (FDR-GC: odds ratio (OR) = 1.655; 95%CI, 1.153-2.376; FDR-nGC: OR = 1.984; 95%CI, 1.122-3.506) than those with FDR-nC. The younger the age at which FDRs were diagnosed with GC, the more likely the participants were to develop AG/IM (Ptrend = 0.019). The risk of precursors to GC was higher in participants whose FDR-GC was the mother than in those whose FDR-GC wa...Continue Reading

References

May 1, 1991·Journal of Gastroenterology and Hepatology·A B Price
Jun 8, 2001·International Journal of Cancer. Journal International Du Cancer·P K DhillonJ F Fraumeni
Mar 25, 2006·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Marco BerniniGiovanni de Manzoni
Jun 10, 2006·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·K EtoM Urashima
Jan 9, 2007·Journal of Clinical Epidemiology·Francesca BraviCarlo La Vecchia
Jun 21, 2008·International Journal of Cancer. Journal International Du Cancer·Roberto FoschiEva Negri
Jun 6, 2009·World Journal of Gastroenterology : WJG·Xue-Fu ZhouHui Wu
Nov 6, 2009·British Journal of Cancer·M YaghoobiS A Narod
Feb 24, 2010·International Journal of Cancer. Journal International Du Cancer·Carlos A GonzálezJosé Miguel Sanz-Anquela
May 12, 2011·Journal of Gastroenterology and Hepatology·Yu Bai, Zhao-Shen Li
Sep 24, 2011·World Journal of Gastroenterology : WJG·Jung Min KangBe Long Cho
Feb 19, 2013·Journal of the American Geriatrics Society·Mara A SchonbergEllen P McCarthy
May 28, 2013·Journal of Medical Genetics·Patrick R BenusiglioOlivier Caron
Oct 15, 2013·Journal of Gastroenterology and Hepatology·Eun Jeong GongMin-Ju Kim
Apr 29, 2015·World Journal of Gastroenterology : WJG·Hee-Won KwakYoung-Woo Kim
Mar 5, 2016·Gastrointestinal Endoscopy·Gwang Ha KimJoo Ha Hwang
Aug 23, 2016·Gastroenterology Clinics of North America·Elena M Stoffel
Nov 4, 2016·The Korean Journal of Internal Medicine·Yoon Jin Choi, Nayoung Kim
Dec 13, 2016·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Elizabeth DongBechien U Wu
May 24, 2017·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Massimo RuggeDavid Y Graham
Feb 20, 2018·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Minkyo SongCharles S Rabkin
May 1, 2018·International Journal of Cancer. Journal International Du Cancer·Liming ShaoXinliang Lu
Dec 7, 2018·The Lancet. Gastroenterology & Hepatology·Paul C Lott, Luis G Carvajal-Carmona
Jul 31, 2019·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Aaron P Thrift, Hashem B El-Serag
Mar 15, 2020·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Rosa T van der KaaijJohanna W van Sandick

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Methods Mentioned

BETA
biopsy
dissection
biopsies

Software Mentioned

SPSS

Related Concepts

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Atrophic Gastritis

Atrophic Gastritis is a process where gastric glandular cells are lost and replaced with firbous tissues, as a result of chronic inflammation. Learn more about Atrophic Gastritis here.