Abstract
Diabetes mellitus type 2 (DM2) patients have higher risk to be infected with parenterally transmitted viruses, like hepatitis B or C virus. This study aims to determine HBV and HCV infection prevalence in DM2 patients from Northeast and Southeast Brazil. A total of 537 DM2 patients were included, 194 (36.12%) males and 343 (63.87%) females, with mean age of 57.13±11.49 years. HBV and HCV markers were determined using serological and molecular analysis, and risk factors were evaluated in a subgroup from Southeast (n = 84). Two HBV acute (HBsAg+/anti-HBc -) and one HBV chronic case (HBsAg+/anti-HBc+) were found. Six individuals (1.1%) were isolated anti-HBc, 37 (6.9%) had HBV infection resolved (anti-HBc+/anti-HBs+), 40 (7.4%) were considered HBV vaccinated (anti-HBc-/anti-HBs+). Thirteen patients (2.42%) had anti-HCV and 7 of them were HCV RNA+. In the subgroup, anti-HBc positivity was associated to age and anti-HCV positivity was associated to age, time of diabetes diagnosis, total bilirubin, indirect bilirubin, alkaline phosphatase at bivariate analysis, but none of them was statistically significant at multivariate analysis. As conclusion, low prevalence of HBV and high prevalence HCV was found in DM2 patients.
References
May 5, 1999·Diabetic Medicine : a Journal of the British Diabetic Association·A SotiropoulosS I Pappas
Dec 21, 2002·Transplantation Proceedings·E Y HirakauvaJ O M Pestana
May 13, 2006·Journal of the Chinese Medical Association : JCMA·Hua-Fen ChenHsin-Yu Lee
Jun 30, 2006·International Journal of Clinical Practice·S OcakI Emir
Jun 17, 2008·The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases·Luce Marina Freires Corrêa da CostaFrancisco José Dutra Souto
Aug 1, 2008·Journal of Investigative Medicine : the Official Publication of the American Federation for Clinical Research·Aynur GulcanYusuf Akcan
Sep 17, 2008·European Journal of Gastroenterology & Hepatology·Jean-François CadranelDominique Capron
Jan 14, 2009·World Journal of Gastroenterology : WJG·Diego Garcia-CompeanHector Maldonado-Garza
Feb 11, 2010·Journal of Diabetes Science and Technology·Nicola D Thompson, Joseph F Perz
Oct 18, 2011·Journal of Infection and Public Health·Wassim ChehadehWidad Al-Nakib
Jan 31, 2012·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·L F GrecaJ L Gross
Apr 25, 2012·World Journal of Gastroenterology : WJG·Cho NaingMala Maung
Feb 5, 2013·BMC Infectious Diseases·Leila M M B PereiraRicardo A A Ximenes
May 2, 2013·The International Journal on Drug Policy·Marcelo Santos CruzBenedikt Fischer
Jun 12, 2014·Journal of Medical Virology·Livia Melo VillarElisabeth Lampe
Jun 17, 2014·The Pan African Medical Journal·Daniel MekonnenAdane Mihret
Oct 21, 2014·Annals of Medical and Health Sciences Research·Rkd EphraimEo Anto
Nov 22, 2014·Journal of Investigative Medicine : the Official Publication of the American Federation for Clinical Research·Huseyin KorkmazLevent Kebapcilar
Jun 28, 2015·BMC Public Health·Clarissa de Matos NascimentoSérgio Viana Peixoto
Dec 2, 2015·Experimental and Therapeutic Medicine·Cuixia CaiWenli Ma
Mar 16, 2016·International Journal of Environmental Research and Public Health·Geane L FloresLivia Melo Villar
Jul 8, 2016·Revista da Escola de Enfermagem da U S P·Clarissa Cordeiro Alves ArreliasMaria Lucia Zanetti
Jul 29, 2016·BMC Health Services Research·Ebtesam M Ba-EssaNasser M Al-Daghri
Dec 9, 2016·Journal of Diabetes Investigation·Jun LuWeiping Jia
Jan 5, 2017·Liver International : Official Journal of the International Association for the Study of the Liver·Mitchell L Shiffman, Nadege T Gunn
Apr 25, 2017·Diabetes Research and Clinical Practice·K OgurtsovaL E Makaroff
Jul 18, 2017·International Journal of Environmental Research and Public Health·Jakeline Ribeiro BarbosaLívia Melo Villar
Aug 10, 2017·Revista Do Instituto De Medicina Tropical De São Paulo·Vanessa Faria CortesLivia Melo Villar
Citations
Jul 21, 2020·World Journal of Hepatology·Cliviany Borges da SilvaLuciana Diniz Silva
Apr 23, 2020·Journal of Family Medicine and Primary Care·Muayad A Merza
Aug 15, 2020·Frontiers in Immunology·Gholamreza DaryaborKurosh Kalantar
Mar 6, 2021·Frontiers in Public Health·Jesús Chávez-ReyesBruno A Marichal-Cancino
Apr 16, 2021·Advanced Drug Delivery Reviews·Chien-Yu LinKun Cheng
Jul 3, 2021·Journal of Clinical Medicine·Pei-Yuan SuFu-Yuan Siao