Prevalence of Hepatitis B Virus Exposure in the Veterans Health Administration and Association With Military-Related Risk Factors.

Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association
Lauren A BesteJason A Dominitz

Abstract

Military veterans have been reported to have higher odds of hepatitis B virus (HBV) exposure after adjustment for demographic factors, family income, and birthplace. It is not clear whether military-related exposures are associated with risk of HBV exposure in veterans. A random sample of veterans receiving care from 1998 through 2000 in the national Veterans' Health Administration system completed a risk factor survey and underwent phlebotomy analysis (N = 1146). Stored serum samples were reanalyzed to determine prevalence of HBV exposure (core antibody positive), infection (surface antigen or DNA positive), and immunity (surface antibody positive, surface antigen negative, and core antibody negative). Associations between military-related risk factors and HBV exposure were assessed using logistic regression. The prevalence values for infection, exposure, and immunity were 0.7% (95% CI, 0.3-1.5), 13.6% (95% CI, 11.5-16.1), and 6.2% (95% CI, 4.7-8.2), respectively. Evidence of HBV exposure was highest among respondents with traditional risk factors (such as drug use or high-risk sexual practices). More than half the individuals with HBV exposure (53%) reported no history of traditional risk factors; of these, 59.5% reported a h...Continue Reading

References

Dec 25, 2004·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Jason A DominitzKeith A Young
Jun 10, 2006·Epidemiologic Reviews·John D GrabensteinRenata J M Engler
Nov 23, 2011·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Kris V KowdleyCarol L Brosgart
Jun 24, 2014·Lancet·Christian TrépoAnna Lok
Aug 8, 2015·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Henry RobertsScott D Holmberg
Apr 6, 2017·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Amanda J NoskaLisa I Backus

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Citations

Jun 3, 2020·The American Journal of Gastroenterology·Joseph K LimIra M Jacobson

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