Prevalence of hepatitis C virus infection according to the year of birth: identification of risk groups

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
K NeukamFederico A Di Lello

Abstract

Hepatitis C virus (HCV) screening according to the year of birth is recommended is some countries based on epidemiological data. The aim of this study was to analyze anti-HCV prevalence among people born between 1905 and 2015 in Argentina. Patients attending a tertiary care hospital in Buenos Aires, Argentina, from 2001 to 2015, who had a determination of anti-HCV, were included. Of 22,079 patients analyzed, 1,152 (5.2%; 95% confidence interval [CI]: 4.9%-5.5%) patients showed positive anti-HCV and 729 (3.3%; 95% CI: 3.1%-3.5%) patients showed detectable viremia. Three risk groups were identified (HCV prevalence): low-risk group-outpatient clinics/emergencies (2.8%); intermediate-risk group-in-patients (8%); and high-risk group-dialysis/transplants (27.2%). In the low-risk group, being born in 1973 or before was identified as a cut-off value for the risk of anti-HCV acquisition (area under the receiver-operator characteristic curve: 75.1 [95% asymptotic CI: 0.732-0.770; p < 0.001]). Ninety-one patients born after 1973 (0.8%) showed positive anti-HCV versus 457 individuals born in 1973 or before (5.8%), p < 0.001. In this group, positive anti-HCV was observed in 252 females (2.1%) and 296 males (4.1%), p < 0.001. In a multivaria...Continue Reading

References

Dec 4, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Mercedes WeissenbacherLiliana Martínez Peralta
Jan 1, 1950·Cancer·W J YOUDEN
Jul 18, 2006·Liver International : Official Journal of the International Association for the Study of the Liver·Gastón R PicchioFederico G Villamil
Jun 18, 2011·Liver International : Official Journal of the International Association for the Study of the Liver·David KershenobichMarcelo Silva
Jul 12, 2011·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·María Sol Dos Ramos FaríasMaría Mercedes Avila
Oct 15, 2013·World Journal of Gastroenterology : WJG·Noemí del PinoJosep Quer
Aug 3, 2014·Journal of Hepatology·Erin GowerHomie Razavi
May 10, 2015·The Lancet Infectious Diseases·V Bhargavi RaoGraham S Cooke
Oct 6, 2015·Annals of Hepatology·Cristina Gómez-GutiérrezNahum Méndez-Sánchez
Feb 26, 2016·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Michael S LyonsKenneth E Sherman
May 31, 2016·World Journal of Hepatology·Ezequiel RidruejoMarcelo O Silva
Dec 23, 2016·Journal of Gastroenterology and Hepatology·Jia-Horng KaoSeung-Woon Paik

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Citations

Feb 23, 2020·Archives of Virology·Livia Melo VillarCarlos Espul

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Methods Mentioned

BETA
Assay
PCR

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SPSS
STATA

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