Prevalence of IgG Antibodies against Human Papillomavirus (HPV) type 6, 11, 16, and 18 Virus-Like Particles in Women of Childbearing Age in Port Harcourt, Nigeria

Journal of Immunoassay & Immunochemistry
I O Okonko, Valentina Ofoedu

Abstract

Most HPV prevalence studies have been carried out in high-resource countries with few studies focused on low-resource regions where highest HPV prevalence in the world occurs. This study reports on prevalence of IgG antibodies against HPVs among women of childbearing age in Port Harcourt, Nigeria. One hundred and eighty-two consented women (age-range 19-45 years) were consecutively recruited. Demographic/behavioral data and 5 mL blood samples were collected from each woman. Plasma of each sample was assayed for HPV-6/11/16/18 virus-like particles using a HPV IgG ELISA kit. The overall anti-HPV prevalence was 4.9% while 7.7% with itching/wound in the private part tested positive. Most (88.9%) of the seropositive women were sexually active. Group-specific seropositivity was low (0.0-10.0%). It also showed that all the 9(100.0%) who tested positive to the HPV responded "yes" to no information on the source of HPV information. Being younger, married, high educational level, religion, and lack of information on HPV were the main correlates of HPV positivity among these women. None was vaccinated and would have been naturally exposed to at least one of HPV-6/11/16/18. With 4.9% seropositivity and lack of information regarding HPV amo...Continue Reading

References

Nov 14, 2001·Lancet·X CastellsaguéP Alonso
Aug 15, 2002·British Journal of Cancer·M MolanoUNKNOWN HPV Study Group HPV Study
Sep 5, 2002·International Journal of Cancer. Journal International Du Cancer·Patti E GravittKeerti V Shah
Jan 15, 2003·Clinical Microbiology Reviews·Eileen M Burd
Feb 5, 2003·Sexually Transmitted Diseases·Hugo De VuystMarleen Temmerman
Feb 6, 2003·International Journal of Cancer. Journal International Du Cancer·Thi Hoang Anh PhamSilvia Franceschi
Aug 5, 2003·Sexually Transmitted Diseases·Elena MatosUNKNOWN Proyecto Concordia Collaborative Group
Aug 20, 2003·International Journal of Cancer. Journal International Du Cancer·Silvia FranceschiRolando Herrero
Oct 2, 2003·Sexually Transmitted Diseases·Silvia de SanjoseF Xavier Bosch
Feb 5, 2004·British Journal of Cancer·J O ThomasS Franceschi
Feb 20, 2004·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Raphael P ViscidiRobert D Burk
Apr 22, 2004·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·R NewtonUNKNOWN Uganda Kaposi's Sarcoma Study Group
Jan 13, 2006·Vaccine·Helen Trottier, Eduardo L Franco
Feb 8, 2006·The Pediatric Infectious Disease Journal·Ian H FrazerLuisa L Villa
Apr 20, 2006·Revista da Associação Médica Brasileira·Cristina Helena RamaCorintio Mariani Neto
Sep 5, 2006·Vaccine·D Maxwell Parkin, Freddie Bray
Sep 23, 2006·International Journal of Cancer. Journal International Du Cancer·Silvia FranceschiNubia Muñoz
Sep 15, 2007·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Gary M CliffordSilvia Franceschi
Nov 7, 2007·Journal of Tropical Pediatrics·I J WangC J Chen
Dec 25, 2007·Sexually Transmitted Diseases·Robert C Brunham, Michael L Rekart
May 1, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Anthony T NewallC Raina MacIntyre
Jun 19, 2008·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Mahboobeh SafaeianRon Gray
Aug 20, 2010·The Journal of General Virology·Zizipho Z A MbulawaAnna-Lise Williamson
Sep 10, 2010·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Salvatore VaccarellaUNKNOWN IARC HPV Prevalence Surveys Study Group
Nov 16, 2010·The Lancet Infectious Diseases·Nienke J VeldhuijzenJanneke Hhm van de Wijgert
Dec 7, 2010·Infectious Agents and Cancer·Clement OkoloGary M Clifford
Jun 2, 2011·International Journal of Cancer. Journal International Du Cancer·Julia C GageMark Schiffman

❮ Previous
Next ❯

Citations

Mar 3, 2020·Frontiers in Cellular and Infection Microbiology·Cameron KleinPeter C Angeletti

❮ Previous
Next ❯

Methods Mentioned

BETA
ELISA

Software Mentioned

SPSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.