Prevalence of Lower-Extremity Arterial Calcification in Patients with Diabetes Mellitus Complicated by Foot Disease at an Urban US Tertiary-Care Center

Journal of the American Podiatric Medical Association
Vanessa CardenasAndrew J Meyr

Abstract

We sought to determine the prevalence of lower-extremity arterial calcification in a cohort of patients with diabetes and associated foot pathology receiving inpatient treatment at an urban US tertiary health-care system. The primary outcome measure was defined as either radiographic evidence of vessel calcification or noninvasive vascular testing that resulted in any reporting of vessel noncompressibility or an ankle-brachial index greater than 1.1. Radiographic evidence of vessel calcification was defined as radiodense calcification in the proximal first intermetatarsal space (deep plantar perforating artery), anterior ankle (anterior tibial artery), or posterior ankle (posterior tibial artery) on dorsoplantar and lateral foot projections. Of the 367 individuals included in the study, 359 underwent radiography, with radiographic evidence of calcification in 192 (53.5%). Noninvasive vascular testing was performed on 265 participants, with any reporting of noncompressibility or an ankle-brachial index greater than 1.1 observed in 153 (57.7%). Ninety-four participants (25.6%) demonstrated evidence of arterial calcification on the radiographs and noninvasive testing, meaning that 251 participants (68.4%) demonstrated evidence of ...Continue Reading

References

Sep 1, 1979·Archives of Surgery·G W GibbonsC Siembieda
Mar 27, 1982·British Medical Journal·M E EdmondsP J Watkins
Sep 1, 1995·Diabetes Research and Clinical Practice·E ChantelauR Jungblut
Sep 8, 2000·Diabetes Care·C HarringtonJ Klitenic
Jun 1, 2002·Journal of Diabetes and Its Complications·Jennifer A MayfieldDouglas G Smith
Dec 6, 2003·Arteriosclerosis, Thrombosis, and Vascular Biology·Matthew A AllisonC Michael Wright
Aug 5, 2006·Vascular Medicine·Antonio SilvestroIris Baumgartner
Mar 5, 2008·Foot & Ankle International·Christopher David SmithMelwyn Pereira
Apr 30, 2008·Diabetes/metabolism Research and Reviews·Andrew J M Boulton
May 17, 2008·Journal of the American College of Cardiology·Raul J GuzmanXiao Qin
Feb 4, 2010·Diabetic Medicine : a Journal of the British Diabetic Association·E B JudeN Tentolouris
Apr 30, 2010·Diabetes Care·Anish SharmaWilliam J Jeffcoate
Mar 17, 2011·Journal of the American Podiatric Medical Association·Ginger S CarlsJames R Christina
Apr 26, 2011·Annals of Vascular Surgery·Dimitri AerdenPierre Van den Brande
May 10, 2011·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Teresa AdragaoMateus Martins Prata
Aug 23, 2011·The International Journal of Lower Extremity Wounds·Ezio Faglia
Jan 21, 2012·Journal of the American College of Cardiology·Faisal A ArainIftikhar J Kullo
Jan 12, 2013·Diabetes Research and Clinical Practice·Raul J GuzmanC Michael Stein
Mar 5, 2013·Calcified Tissue International·Meiting WuCecilia M Giachelli
Nov 28, 2013·The International Journal of Lower Extremity Wounds·Javier Aragón-Sánchez, Jose L Lázaro-Martínez
Feb 11, 2015·The Journal of Foot and Ankle Surgery : Official Publication of the American College of Foot and Ankle Surgeons·Eric LewGeorgeanne Botek
Sep 6, 2015·Diabetes/metabolism Research and Reviews·J R W BrownriggUNKNOWN International Working Group on the Diabetic Foot
Oct 10, 2015·Diabetes/metabolism Research and Reviews·K MarkakisA J M Boulton

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.