PMID: 8591713Sep 1, 1995Paper

Prevalence of macro- and microvascular diseases in non-insulin-dependent diabetic and borderline glucose-intolerant subjects with insulin resistance syndrome

Diabetes Research and Clinical Practice
K KatsumoriY Omori

Abstract

This study was undertaken to ascertain whether patients with insulin resistance syndrome, a cluster of risk factors for coronary artery disease (CAD), are really a high risk population for macro- and microvascular diseases in Japanese NIDDM and borderline glucose-intolerant subjects. A diagnosis of insulin resistance syndrome was made if four of the six following criteria are satisfied: glucose disposal rate < 2.2 mg/kg/min, fasting plasma IRI > 15 microU/ml or peak plasma IRI > 100 microU/ml during meal tolerance test, plasma triglyceride > 150 mg/dl at fasting or > 200 mg/dl after meal, serum HDL-cholesterol < 40 mg/dl, blood pressure > 140 mm Hg systolic and > 90 mm Hg diastolic or treatment with antihypertensive agents, and body mass index (BMI) > 27 for men or > 25 for women. We compared the prevalence of CAD, cerebral vascular disease (CVD), peripheral vascular disease (PVD), retinopathy and nephropathy between the insulin resistance syndrome group (group A, n = 57) and the remaining group (group B, n = 164). Both groups did not differ with respect to age, duration of diabetes, BMI, fasting plasma glucose, HbA1c, composition of NIDDM and borderline glucose-intolerance (BGI) or treatment modality. The prevalence of CAD was...Continue Reading

References

Jan 1, 1992·Journal of Cardiovascular Pharmacology·R A DeFronzo
Feb 21, 1991·The American Journal of Medicine·R W Stout
Mar 14, 1991·The New England Journal of Medicine·M F SaadB V Howard
Feb 1, 1990·Diabetes/metabolism Reviews·W C KnowlerP H Bennett
Mar 1, 1990·Diabetes/metabolism Reviews·M I Harris
Sep 1, 1990·Arteriosclerosis : an Official Journal of the American Heart Association, Inc·S M HaffnerJ K Patterson
Feb 1, 1990·Metabolism: Clinical and Experimental·T PollareC Berne
Dec 1, 1989·European Journal of Clinical Investigation·M LaaksoL Mykkänen
Jun 1, 1989·Diabetes·M A Banerji, H E Lebovitz
Aug 10, 1989·The New England Journal of Medicine·J ErikssonL Groop
Nov 17, 1988·The New England Journal of Medicine·S M HaffnerJ K Patterson
Aug 6, 1987·The New England Journal of Medicine·E FerranniniS Bevilacqua
Apr 1, 1987·The Journal of Clinical Endocrinology and Metabolism·A L SwislockiG M Reaven
Mar 1, 1985·The Journal of Clinical Investigation·M ModanZ Fuchs
Jan 1, 1985·Upsala Journal of Medical Sciences·F LithnerG Hallmans
Feb 9, 1984·The New England Journal of Medicine·C E Mogensen
Jul 1, 1993·Diabetic Medicine : a Journal of the British Diabetic Association·L NiskanenM Uusitupa

❮ Previous
Next ❯

Citations

Jun 21, 2006·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·Jorn-Hon LiuWen-Ling Li
Aug 30, 2006·Clinics in Laboratory Medicine·Zachary T Bloomgarden
Aug 22, 2006·Metabolism: Clinical and Experimental·Marc S Rendell, Lois Jovanovic
Aug 4, 2015·Journal of Diabetes and Its Complications·Shu-Chen KuoFung-Chung Sung
Feb 5, 2003·Current Medical Research and Opinion·Marc RendellPeter Zhang
Apr 29, 2003·Clinical and Experimental Hypertension : CHE·Shigeru NakanoKenzo Uchida
Jul 26, 2011·American Journal of Physiology. Heart and Circulatory Physiology·Yolanda MendizábalEduardo Nava

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Inflammation

Inflammation plays a significant role in the development of cardiovascular diseases, an understanding of these endogenous processes is critical for evaluating the risks and potential treatment strategies. Discover the latest research on cardiovascular inflammation here.

Biomarkers for Type 2 Diabetes

Biomarkers can help understand chronic diseases and assist in risk prediction for prevention and early detection of diseases. Here is the latest research on biomarkers in type 2 diabetes, a disease in which the body is unable to produce or properly use insulin.

Antihypertensive Agents: Mechanisms of Action

Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.

CV Disorders & Type 2 Diabetes

This feed focuses on the association of cardiovascular diseases in patients with type 2 diabetes.