Prevalence of methicillin-sensitive, methicillin-resistant Staphylococcus aureus , and extended-spectrum beta-lactamase-producing Escherichia coli in newborns: a cross-sectional study

The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
K HeiglS Heinze

Abstract

The prevalence of antimicrobial-resistant bacteria and methicillin-sensitive Staphylococcus aureus (MSSA) in healthy newborns and the role of maternal transmission are scarcely discussed. The objective of this study was to evaluate the prevalence of MSSA, MRSA, and ESBL among healthy newborns. Additionally, mother-to-newborn transmission rates were investigated as well as antibiotic susceptibility of MSSA, MRSA, and ESBL isolates. Swabs of 658 newborns and their mothers were collected to investigate the presence of MSSA, MRSA, and ESBL. Swabs were taken from the nose and umbilicus immediately after birth. Additional swabs were taken from the nose, perianal area, and umbilicus 3 days after birth. Samples were screened and further characterized using culture and molecular methods. Prevalence of MSSA, MRSA, and ESBL colonization was 10.9, 0.5, and 2.6%, respectively. There was no association between the colonization status of the newborn and infections at any time point. Mother-to-newborn transmission rates (confirmed by PFGE) were 53.6% for MSSA/MRSA and 100% for ESBL. Maternal carriage of MSSA, MRSA, or ESBL was a risk factor for colonization of the newborn. Some isolates were resistant to the antibiotics recommended for therapy...Continue Reading

References

Nov 28, 2002·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Philip L GrahamLisa Saiman
Dec 10, 2003·Journal of Clinical Microbiology·Sharon J PeacockNicholas P J Day
Aug 28, 2009·Journal of Perinatology : Official Journal of the California Perinatal Association·A J CareyL Saiman
Sep 1, 2009·American Journal of Obstetrics and Gynecology·Janet I AndrewsDaniel J Diekema
Dec 23, 2011·The Pediatric Infectious Disease Journal·Eyal LeshemGili Regev-Yochay
Apr 5, 2012·Pediatrics·Natalia Jimenez-TruqueC Buddy Creech
Jul 21, 2012·Journal of Clinical Microbiology·Frieder SchaumburgUNKNOWN study group
Dec 4, 2013·Antimicrobial Agents and Chemotherapy·Giuseppe ValenzaChristiane Höller
Mar 13, 2014·Pediatrics·Fainareti N ZervouEleftherios Mylonakis
Feb 11, 2015·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Deepak SharmaSrinivas Murki
Oct 29, 2015·Journal of Perinatology : Official Journal of the California Perinatal Association·S RettedalK Øymar
Dec 27, 2016·International Journal of Medical Microbiology : IJMM·Karsten BeckerUNKNOWN Prevalence of Multiresistant Microorganisms PMM Study
May 6, 2017·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·M ZamfirC Herr
Jan 14, 2018·The Journal of Hospital Infection·D DaninoA Borer
Sep 7, 2018·Health & Place·Sharon CampbellFay H Johnston

❮ Previous
Next ❯

Citations

Jul 3, 2021·Microorganisms·Lital Ashtamkar MatokAvi Peretz

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carbapenems

Carbapenems are members of the beta lactam class of antibiotics and are used for the treatment of severe or high-risk bacterial infections. Discover the latest research on carbapenems here.

Carbapenems (ASM)

Carbapenems are members of the beta lactam class of antibiotics and are used for the treatment of severe or high-risk bacterial infections. Discover the latest research on carbapenems here.