Prevalence of Mycoplasma pneumoniae: a cause for community-acquired infection among pediatric populaztion

Nigerian Journal of Clinical Practice
F Q ChenC B Bi

Abstract

Atypical pneumonia caused by Mycoplasma pneumoniae is a leading cause of mortality among the pediatric age group. Our study was designed to know the prevalence of M. pneumoniae in children with community-acquired pneumonia and the involvement in the cytoadherence to the respiratory epithelium by M. pneumoniae using electron microscopy and immuno-gold labeling technique. A total of 152 children of 1 month to 12 years of age of both sexes attending Hebei Provincial People's Hospital, Shijiazhuang, Hebei with diagnosed pneumonia were included in the study. Out of 152 children 84 (55.3%) were males, and 68 (44.7%) were females. The mean age of the patients in the control group (50 patients) was 18.5 ± 3 months with 31 (62%) males and 19 (38%) females. IgM antibodies against M. pneumoniae were positive in 84 (55.3%) males and 68 (44.7%) females. Out of 50 patients 9 (18%) were found to positive for IgM M. pneumoniae antibodies of which four (44.4%) males and 5 (55.5%) females were positive. Our study observed that the gold particles were clustered on the filamentous extension of the tip of the cells. Out of 152 serum samples subjected to particle agglutination assay 138 (90.7%) were positive 1:320 titer, 9 were >1:80 and 3 showed ti...Continue Reading

Citations

May 6, 2016·Frontiers in Microbiology·Gretchen L ParrottJiro Fujita
Jul 24, 2015·Journal of Clinical Microbiology·Rebecca J BrownVictoria J Chalker
Jun 1, 2016·Allergologia et immunopathologia·J CarceyJ A Castro-Rodriguez

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