Prevalence of nephropathy in black patients with type 2 diabetes mellitus

American Journal of Nephrology
James GitterBarry I Freedman

Abstract

The prevalence of nephropathy in black patients with type 2 diabetes mellitus is poorly defined. We performed a cross-sectional analysis of 98 unrelated and unselected black type 2 diabetic patients treated in indigent care internal medicine clinics to determine the prevalence of proteinuria and nephropathy. Serum creatinine, blood urea nitrogen, urine albumin and urine creatinine concentrations were measured. A Spearman's rank correlation was computed to test for a relationship between diabetes duration and continuous outcomes. For binary outcomes, an odds ratio and 95% confidence interval were computed for a change of 10 years diabetes duration based on logistic regression. Cases were 61% female, and had mean (+/- SD) age 59.9 +/- 12.5 years, diabetes duration 12.6 +/- 9.4 years, body mass index 32.4 +/- 9.3 kg/m(2), hemoglobin A1C (HbA1C) 9.2 +/- 2.3%, and serum creatinine concentration 1.60 +/- 1.1 mg/dl. For continuous variables, diabetes duration was positively associated with albuminuria (r = 0.31; p = 0.0017), serum creatinine (r = 0.36; p = 0.0003) and blood urea nitrogen concentration (r = 0.36; p = 0.0003). For binary variables, cases with longer diabetes duration were at increased risk for urinary albumin:creatinine...Continue Reading

Citations

May 11, 2012·Current Diabetes Reports·Nicholette D Palmer, Barry I Freedman
Dec 15, 2010·Kidney International·Caitrin W McDonoughDonald W Bowden
Aug 30, 2002·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Scott G SatkoBarry I Freedman
Jul 7, 2016·The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology·Rajavel VaratharajanPitchai Balakumar
Apr 10, 2004·Current Opinion in Nephrology and Hypertension·Scott G Satko, Barry I Freedman

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