Prevalence of non-tuberculous mycobacterial infections among tuberculosis suspects in Nigeria

PloS One
Gambo AliyuWilliam Blattner

Abstract

Nigeria is ranked in the top five countries for tuberculosis deaths worldwide. This study investigated the mycobacterial agents associated with presumptive clinical pulmonary tuberculosis (TB) in Nigeria and evaluated the pattern and frequency of mycobacterial infections over twelve calendar months period. Sputum samples from 1,603 consecutive new cases with presumptive diagnosis of TB were collected from August 2010 to July 2011. All sputum samples were incubated for detection of mycobacterial growth and those with positive acid fast bacilli (AFB) growth were tested to detect mycobacterium tuberculosis (MTB) complex and characterized to differentiate between MTB complex species. Cultures suggestive of Non-tuberculous mycobacterial infections (NTM) were sub-cultured and characterized. Of the 1,603 patients screened, 444 (28%) culture-positive cases of pulmonary tuberculosis were identified. Of these, 375 (85%) were due to strains of MTB complex (354 cases of M. tuberculosis, 20 M. africanum and one case of M. bovis) and 69 (15%) were due to infection with NTM. In contrast to the MTB complex cases, the NTM cases were more likely to have been diagnosed during the calendar months of the Harmattan dust season (OR = 2.34, 1.28-4.29;...Continue Reading

References

Jun 1, 1988·The American Review of Respiratory Disease·M TsukamuraA Kuze
Jan 1, 1984·Transactions of the Royal Society of Tropical Medicine and Hygiene·F I AnjorinY M Fakunle
Jun 1, 1993·Journal of Clinical Pathology·R C Ellis, L A Zabrowarny
May 1, 1993·Kansenshōgaku zasshi. The Journal of the Japanese Association for Infectious Diseases·K UematsuK Ishikawa
Oct 30, 1999·The European Respiratory Journal·V L Kinnula
Oct 10, 2002·Clinics in Chest Medicine·Theodore K Marras, Charles L Daley
Jun 7, 2003·Journal of Clinical Microbiology·Sara Ngo Niobe-EyangohM Cristina Gutierrez
Feb 8, 2005·PLoS Medicine·Benjamin SultanSerge Janicot
Dec 8, 2005·Journal of Clinical Microbiology·Patricia C A M BuijtelsDick van Soolingen
Jan 5, 2006·Journal of Clinical Microbiology·Simeon CadmusStephen V Gordon
Feb 6, 2007·American Journal of Respiratory and Critical Care Medicine·David E GriffithUNKNOWN Infectious Disease Society of America
Jan 24, 2008·Industrial Health·Daniela PelclováPavlína Klusácková
Jan 30, 2008·Free Radical Biology & Medicine·Raymond F HamiltonAndrij Holian
Feb 12, 2008·The Journal of Nutrition, Health & Aging·N R SahyounM K Serdula
Jun 28, 2008·Science·Leslie Roberts
Jan 1, 2009·Emerging Infectious Diseases·John A CrumpDick van Soolingen
Apr 21, 2009·Bulletin of the World Health Organization·Yohannes KinfuDavid B Evans
May 21, 2009·The Journal of Immunology : Official Journal of the American Association of Immunologists·Rajamouli PasulaWilliam J Martin
Jul 25, 2009·American Journal of Respiratory and Critical Care Medicine·Patama MonkongdeeJay K Varma
Oct 17, 2009·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·P C A M BuijtelsD van Soolingen
Nov 3, 2009·American Journal of Industrial Medicine·Harriet H ParkRodney I Ehrlich
May 4, 2010·PLoS Neglected Tropical Diseases·Krishnamoorthy Gopinath, Sarman Singh
Jul 17, 2010·Scandinavian Journal of Infectious Diseases·António AmorimEdna Pereira
May 1, 2007·Indian Journal of Occupational and Environmental Medicine·Rajnarayan R TiwariHabibullah N Saiyed
Jan 20, 2012·Emerging Infectious Diseases·Michel K GomgnimbouChristophe Sola
Apr 18, 2012·The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease·B TraoreM A Polis
Dec 13, 2012·The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease·M DaraUNKNOWN International Union Against Tuberculosis and Lung Disease

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Citations

Feb 18, 2016·Emerging Infectious Diseases·Ravikiran M RajuEric J Rubin
Feb 18, 2016·Emerging Infectious Diseases·Aditya SharmaEleanor S Click
Jul 16, 2015·Tuberculosis and Respiratory Diseases·Eduardo Hernández-GarduñoSalvador Ayón-Garibaldo
Mar 16, 2016·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Jason E StoutWing Wai Yew
Apr 15, 2016·Scientific Reports·N F EgbeB M de C Bronsvoort
Apr 4, 2015·American Journal of Respiratory and Critical Care Medicine·Daniel P BoyleChao Qi
Nov 8, 2015·BMC Infectious Diseases·Pascalina Chanda-KapataMartin P Grobusch
Dec 24, 2017·Tropical Animal Health and Production·Victor O AkinseyeSimeon I B Cadmus
Jul 30, 2017·Applied and Environmental Microbiology·Kenneth C MalcolmJerry A Nick
Jul 8, 2016·Tropical Medicine & International Health : TM & IH·Stephanie BjerrumIsik Somuncu Johansen
Sep 8, 2017·African Journal of Laboratory Medicine·Gambo AliyuAlash'le Abimiku
May 16, 2018·Antimicrobial Agents and Chemotherapy·Jingjing LuoHairong Huang
Aug 20, 2019·The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases·Desak Nyoman Surya Suameitria DewiSohkichi Matsumoto
Oct 28, 2020·The Indian Journal of Medical Research·Surendra K Sharma, Vishwanath Upadhyay

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