Prevalence of novel repeat sequences in and around the P1 operon in the genome of Mycoplasma pneumoniae

Gene
S D ColmanK F Bott

Abstract

The presence of numerous different repetitive elements in the genome of Mycoplasma pneumoniae has been documented by several laboratories. One which we previously identified, denoted as SDC1, has now been further characterized, verified to be distinct from those discussed in previous publications and shown to lack homology to several other species of Mycoplasma when tested under our stringency conditions. As many as eight versions of the SDC1-type repeat, which is more than 400 bp long, are scattered throughout the genome of M. pneumoniae. The prototype for SDC1 is found within a gene encoding a putative 130-kDa membrane-binding protein lying just downstream from the gene encoding the cytadhesin protein P1. In fact, all of the reported M. pneumoniae repetitive elements have at least one representative either within or adjacent to the P1 operon; many if not all of these lie within open reading frames. The function of these repetitive elements is still unclear.

References

Dec 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·F SangerA R Coulson
May 1, 1977·The Journal of Experimental Medicine·P C HuJ B Baseman
Sep 12, 1988·Nucleic Acids Research·R Wenzel, R Herrmann
Sep 12, 1988·Nucleic Acids Research·R Wenzel, R Herrmann
Sep 1, 1985·Journal of General Microbiology·G BertoloniG Jori
Jan 1, 1971·The Journal of Infectious Diseases·F W DennyW P Glezen
Jun 13, 1966·Biochemical and Biophysical Research Communications·D T Denhardt
Nov 15, 1980·Analytical Biochemistry·G E Smith, M D Summers
Jul 1, 1980·Cell·M P Calos, J H Miller
Jul 1, 1983·Analytical Biochemistry·A P Feinberg, B Vogelstein
Sep 1, 1983·Proceedings of the National Academy of Sciences of the United States of America·R E Reed, S Altman
Jan 11, 1984·Nucleic Acids Research·J DevereuxO Smithies

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Citations

Dec 14, 2005·Transactions of the Royal Society of Tropical Medicine and Hygiene·Yichun LiuEng Eong Ooi
Nov 11, 1991·Nucleic Acids Research·S N PetersonC A Hutchison
Feb 1, 1991·Molecular Microbiology·B SperkerR Herrmann
Mar 1, 2012·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Kensei GotohTakao Ozaki
Jul 1, 1992·Journal of Bacteriology·J R Lupski, G M Weinstock
Feb 1, 1992·Journal of Bacteriology·K Dybvig, A Woodard
Apr 1, 1994·Clinical Microbiology Reviews·A van Belkum
Dec 1, 1993·Journal of Bacteriology·S N PetersonC A Hutchison
Sep 1, 1994·Journal of Bacteriology·K RulandR Herrmann
Dec 1, 1990·Microbiological Reviews·S Krawiec, M Riley

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