Abstract
Background: Oral clefts (OCs) are common human birth defects. Children with OCs in underdeveloped regions are more likely to suffer from poverty and hardship in their future lives. Here, we attempted to estimate the prevalence of OCs among live births in Gansu Province in 2008 to understand the epidemiologic pattern of the disease. Methods: A cross-sectional study was conducted from January 2008 to December 2008 in Gansu Province. The live births delivered between January and December 2008 with OCs were investigated through face-to-face questionnaire survey. Results: A total of 468 infants with OCs were identified among 347,137 live births in 2008 in Gansu Province, which yielded a prevalence of 1.35 per 1000 live births. The majority of these cases were CL (cleft lip) (prevalence = 0.85 per 1000 live births), and the prevalence of CLP (cleft lip and palate) and CP (cleft palate) was 0.34 and 0.11 per 1000 live births, respectively. We also found that the prevalence of OCs in Jiayuguan (3.39 per 1000 live births) and Dingxi (2.71 per 1000 live births) was higher than those of other cities in Gansu Province. Additionally, we failed to detect significant correlation between economic conditions of the cities and the prevalence of ...Continue Reading
References
Aug 2, 2002·Facial Plastic Surgery : FPS·Nina Wantia, Gerhard Rettinger
Mar 22, 2003·Annals of Tropical Paediatrics·Ning ChengHueiyen He
May 27, 2005·Current Opinion in Genetics & Development·Astanand Jugessur, Jeffrey C Murray
Sep 22, 2006·The Cleft Palate-craniofacial Journal : Official Publication of the American Cleft Palate-Craniofacial Association·Margaret E CooperMary L Marazita
Jul 27, 2007·Orthodontics & Craniofacial Research·Peter Mossey
Aug 20, 2009·Birth Defects Research. Part A, Clinical and Molecular Teratology·Li DaiYawei Zhang
Sep 15, 2009·Lancet·Peter A MosseyWilliam C Shaw
Oct 31, 2009·World Journal of Surgery·Charles MockKelly McQueen
Dec 17, 2009·Annals of Epidemiology·Lynne C MesserPeter H Langlois
Jan 12, 2010·World Journal of Surgery·William P MageeKristin Ward Hatcher
Feb 19, 2011·Nature Reviews. Genetics·Michael J DixonJeffrey C Murray
Apr 15, 2011·Advances in Dental Research·P A MosseyJ Little
Jun 30, 2012·Plastic and Reconstructive Surgery·Christopher D HughesRichard Silverman
Nov 27, 2014·Plastic and Reconstructive Surgery. Global Open·Rochelle R KlingEthylin Wang Jabs
Oct 1, 2015·PloS One·Leilei PeiHong Yan
Dec 17, 2015·World Journal of Surgery·Dan PoenaruScott Corlew
Oct 21, 2016·The Journal of Craniofacial Surgery·Benjamin B MassenburgNivaldo Alonso
Jun 22, 2017·Birth Defects Research·Mengying WangTerri H Beaty
Citations
Dec 5, 2019·The Cleft Palate-craniofacial Journal : Official Publication of the American Cleft Palate-Craniofacial Association·Rengifo Reina Herney Alonso, Guarnizo Peralta Stefany Brigetty
Mar 22, 2021·Reproductive Biology and Endocrinology : RB&E·Huan WuYunxia Cao
May 26, 2021·Journal of Stomatology, Oral and Maxillofacial Surgery·Nader SalariMasoud Mohammadi
Aug 4, 2021·BMJ Open·Yingxian ZhuFenghua Liu