Prevalence of oral mucosal lesions in adults undergoing highly active antiretroviral therapy in Hong Kong

Journal of Investigative and Clinical Dentistry
Mahendra PereraPatrick Li

Abstract

Highly active antiretroviral therapy (HAART) has altered the prevalence and incidence of oral mucosal lesions of HIV infection. Recent reports show a variation in the prevalence of oral mucosal lesions in different population groups. Understanding the prevalence of these lesions is of paramount importance in the efficient delivery of dental care to such cohorts. The aim of the present study was to investigate the prevalence of oral mucosal lesions and salivary parameters during HAART in an ethnic Chinese cohort in Hong Kong. A cross-sectional estimation of the prevalence of oral mucosal lesions was carried out in 101 HIV-infected ethnic Chinese in Hong Kong using the European Community-Clearinghouse classification. The prevalence of oral mucosal lesions was more common in patients who were classified at baseline as Centers for Disease Control (CDC) C3 category than CDC A2, A3, B2, and B3 (P < 0.05). An overall prevalence of 1.98% was observed for oral Kaposi's sarcoma. Additionally, the HIV group on HAART (0.37 ± 0.23 mL/min) had significantly lower salivary flow rates (P < 0.01) compared with the healthy group (0.49 ± 0.15 mL/min). Although HAART appears to markedly reduce the prevalence of oral mucosal lesions during the cour...Continue Reading

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Citations

Aug 14, 2012·Journal of Investigative and Clinical Dentistry·Lakshman Samaranayake
Jul 19, 2018·Journal of Investigative and Clinical Dentistry·Asma El Howati, Anwar Tappuni

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