Abstract
We aimed to estimate the frequency of overlap of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) with systemic autoimmune diseases. Retrospective single-center study to identify patients with AAV diagnosis and concomitant autoimmune systemic diseases, simultaneously, before or after the diagnosis of AAV. Sociodemographic characteristics, such as comorbidities; follow-up time; type of AAV; disease duration; relapses; treatment and response; clinical, serological, and histological characteristics; disease activity and damage; prognosis; dialysis requirements, and death were assessed. Twenty-eight of two hundred and forty-seven patients (11.3%) with AAV had a concomitant diagnosis of autoimmune disease. The predominant AAV type was renal-limited vasculitis (39%), followed by granulomatosis with polyangiitis (29%), mycroscopic polyangiitis (25%), and eosinophilic granulomatosis with polyangiitis (7%). Mean age at AAV diagnosis was 50 ± 17 years and 24/28 were ANCA positive. The main clinical manifestations were renal (79%), otorhinolaryngologic (43%), and pulmonary and peripheral neuropathy (32%). Sixteen patients (57%) experienced partial or total remission at a median follow-up of 34 months, and four patien...Continue Reading
References
Feb 1, 1992·British Journal of Rheumatology·L R WedderburnS R Rudge
Feb 11, 1999·British Journal of Rheumatology·J FontM Ingelmo
Sep 30, 2003·Lupus·D Sen, David A Isenberg
Jul 30, 2004·Clinical & Experimental Ophthalmology·Kenneth G-J OoiEwan G Kemp
Aug 30, 2005·Autoimmunity·Tatiana Sofía Rodríguez-Reyna, Donato Alarcón-Segovia
Feb 14, 2006·Annals of the Rheumatic Diseases·G Hernández-MolinaJ C Crispín
Jul 17, 2007·Medicine·Manuel Ramos-CasalsMunther A Khamashta
Oct 24, 2007·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Frank BienaiméJean-Philippe Rougier
May 1, 2009·Kidney International·Feng YuMing-hui Zhao
May 18, 2010·Joint, Bone, Spine : Revue Du Rhumatisme·Juan Jakez-OcampoLuis Llorente
Nov 13, 2010·The European Respiratory Journal·P GuilpainF Batteux
Jul 2, 2011·Journal of the American Society of Nephrology : JASN·Yassaman RaissianLynn D Cornell
Dec 23, 2011·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Alexandre BelotPierre Quartier
Jul 20, 2012·The New England Journal of Medicine·Paul A LyonsKenneth G C Smith
Dec 25, 2012·Medicine·Thomas QuéméneurEric Hachulla
Jul 9, 2013·Rheumatology·Emma C Derrett-SmithChristopher P Denton
Sep 3, 2013·Human Pathology·Sing Yun ChangEunhee S Yi
Feb 11, 2015·SpringerPlus·Juliana Draibe, Alan D Salama
Mar 6, 2015·Current Rheumatology Reports·Rodolfo Perez-Alamino, Hernán Maldonado-Ficco
Apr 29, 2015·Autoimmunity Reviews·Dewi GuellecUNKNOWN CRI (Club Rhumatismes et Inflammation) and the French Vasculitis Study Group
Jun 30, 2015·Case Reports in Nephrology and Dialysis·Keiichi KubotaYosifumi Ubara
Mar 10, 2016·Clinical Rheumatology·J F Mendoza RincónJ Ramírez Bello
Jun 4, 2016·Internal Medicine Journal·C CampochiaroM Tresoldi
Jun 4, 2016·Medicine·Pierre-Andre JarrotNoemie Jourde-Chiche
Aug 26, 2016·Medicine·Emanuel Della-TorreClaudio Doglioni
Sep 14, 2016·Immunologic Research·Amandine TuberyClaire I Daïen
Oct 1, 2016·Rheumatology·Juan Carlos ZentenoLuis Felipe Flores-Suárez
Oct 14, 2016·European Journal of Rheumatology·Christian Pagnoux
May 12, 2017·Journal of Nephropathology·Mário GóisFernando Nolasco
Jun 9, 2017·The Tohoku Journal of Experimental Medicine·Masaru AndoJun-Ichi Kadota
Aug 7, 2017·Autoimmunity Reviews·François-Xavier DanlosUNKNOWN French Vasculitis Study Group
Citations
Aug 17, 2019·Journal of Clinical Medicine·Fanny GuibertJean-François Augusto
Dec 29, 2020·The American Journal of Medicine·Fabian LeoChristian Grohé
Jan 29, 2021·Case Reports in Rheumatology·Hiroyuki HounokiKazuyuki Tobe
Feb 7, 2021·Rheumatology·Eduardo Martín-Nares, Gabriela Hernandez-Molina
Apr 2, 2021·European Journal of Medical Research·Rui WuJing Zhu
Apr 20, 2021·Frontiers in Medicine·Riccardo CapecchiPaola Migliorini
Jun 16, 2021·BMC Nephrology·Yoshitaka FurutoYuko Shibuya
Aug 25, 2021·Zeitschrift für Rheumatologie·Aaron JucheAndreas Krause
Aug 31, 2021·Clinical Reviews in Allergy & Immunology·Marco FolciEnrico Brunetta
Nov 18, 2021·CEN Case Reports·Yoichi IwafuchiIchiei Narita