Prevalence of oxygen desaturation and use of oxygen at home in adults at sea level and at moderate altitude

The European Respiratory Journal
R Perez-PadillaProyecto Latinoamericano de Investigacion en Obstruccion Pulmonar (PLATINO) group

Abstract

The aim of this study was to determine the prevalence of oxygen desaturation in adults aged>or=40 yrs as altitude above sea level increases. A population-based, cross-sectional study with a multistage cluster sampling of 1,063 subjects from metropolitan Mexico City (Mexico; 2,240 m above sea level), 1,357 from Caracas (Venezuela; 950 m) and 943 from Montevideo (Uruguay; 35 m). The mean of six measurements of arterial oxygen saturation (SP,O2) was estimated using a pulse oximeter. Mean SP,O2 decreased with altitude. No subject from Montevideo had a mean SP,O2<or=88%. Prevalence of subjects with SP,O2<or=88%, a common criterion used for oxygen prescription, was 1.0% in Caracas and 6.0% in Mexico City. Additional predicting factors for hypoxaemia in multiple regression models were age, body mass index and a low forced expiratory volume in one second as a percentage of the predicted value. In Mexico City and Caracas, <10% of the hypoxaemic subjects reported use of domiciliary oxygen, whereas at least half of the subjects reporting use of oxygen at home had a resting SP,O2>88%. In conclusion, the prevalence of hypoxaemia was closely related to altitude. Priorities for oxygen prescription must be defined in moderate altitudes because...Continue Reading

Citations

Jul 2, 2011·High Altitude Medicine & Biology·Antonio Cabrera de LeónUNKNOWN CDC of the Canary Islands Group
Feb 22, 2012·Archivos de bronconeumología·Rafael Laniado-LaborinOtto Bauerle
Nov 15, 2011·Archivos de bronconeumología·Rogelio Pérez-PadillaLuis Torre-Bouscoulet
Nov 9, 2016·Frontiers in Physiology·David MonteroCarsten Lundby
Jan 19, 2010·Veterinary Pathology·K ShinyaY Kawaoka
Jul 17, 2014·Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia·Rogelio Pérez-PadillaAlvaro Augusto Cruz
Feb 12, 2019·Annals of Global Health·Rogelio Perez-Padilla, Ana Maria B Menezes
Jan 6, 2021·Tropical Medicine and Health·Hiroaki ArimaTaro Yamamoto
Jun 1, 2021·Archivos de bronconeumología·Wilmer Madrid-MejíaLuis Lozano-Martínez
Jun 3, 2021·Life·Rosario Fernández-Plata On Behalf Of The Mexican Translational Research Hypoxemia Working Group

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