Prevalence of parvovirus B19 infection in patients infected with human immunodeficiency virus

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
A M van Elsacker-NeileA C Kroes

Abstract

Parvovirus B19 infection may cause chronic anemia in human immunodeficiency virus (HIV)-infected hosts. Small-scale studies and case reports have suggested that parvovirus B19 infection is a significant cause of anemia in HIV-infected patients. We studied single serum samples from 317 consecutive HIV-infected patients with use of parvovirus B19-specific serology and polymerase chain reaction for detection of viral DNA. Anemia was noted in 176 patients (55.5%); 126 (39.9%) had < 0.10 x 10(9) CD4+ cells/L. In this study group, 191 (60.3%) of the patients were positive for parvovirus B19 IgG. Seroprevalence rates did not differ between patients with low and higher CD4+ cell counts or between anemic and nonanemic patients. Parvovirus B19 DNA was detected in none of the sera. In a control group of 226 healthy male blood donors, the seroprevalence of parvovirus B19 IgG was 68.1%; two IgG-positive sera also contained parvovirus B19 DNA. This study demonstrates that chronic parvovirus B19 infection should not be considered a frequent cause of anemia in HIV-infected individuals.

Citations

Jan 25, 2000·Journal of Clinical Laboratory Analysis·H Boggino, D A Payne
Sep 21, 2002·AIDS Patient Care and STDs·P R Koduri
Mar 17, 2015·Journal of Medical Virology·Kayhan AzadmaneshAmitis Ramezani
Apr 19, 2012·Memórias do Instituto Oswaldo Cruz·Kátia Martins Lopes de AzevedoSolange Artimos de Oliveira
Oct 31, 2009·Memórias do Instituto Oswaldo Cruz·Kátia Martins Lopes de AzevedoSolange Artimos de Oliveira
Jul 19, 2001·Revista Da Sociedade Brasileira De Medicina Tropical·F S AguiarJ P Nascimento
Sep 5, 2006·Memórias do Instituto Oswaldo Cruz·Sérgio SetúbalJussara Pereira do Nascimento
May 16, 2001·Journal of Investigative Medicine : the Official Publication of the American Federation for Clinical Research·R D Semba, G E Gray
Nov 3, 2017·Journal of Medical Microbiology·Mauro Sebastian PedrantiMaria Pilar Adamo
May 9, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Raffaele Badolato
May 29, 1999·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·B Barton Rogers
Apr 10, 2014·Memórias do Instituto Oswaldo Cruz·Renata Freire Alves PereiraSolange Artimos de Oliveira
Dec 22, 2020·Terapevticheskiĭ arkhiv·A A PetrenkoA V Pivnik

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