Prevalence of Pelvic Vein Pathology in Patients with Cryptogenic Stroke and Patent Foramen Ovale Undergoing MRV Pelvis

Cerebrovascular Diseases
Marcey OsgoodNils Henninger

Abstract

A substantial proportion of ischemic strokes has no any identified underlying cause. Notably, the prevalence of a patent foramen ovale (PFO) is increased in cryptogenic stroke (CS) populations, which may serve as a conduit for paradoxical emboli originating from deep vein thrombosis (DVT) including the pelvic veins. Yet, there are no published guidelines for the assessment of pelvic veins as part of the stroke workup and few studies have systematically investigated pelvic veins as a potential source for paradoxical emboli in CS patients. Further, there is a relative paucity of data regarding pelvic DVT in CS and results have been conflicting. Hence, we sought to determine the prevalence of pelvic DVT in select CS patients with PFO who underwent magnetic resonance venography (MRV). We retrospectively identified patients (n = 50) who underwent contrast-enhanced pelvic MRV at the discretion of the treating physician for the evaluation of CS in the presence of a PFO during hospitalization at a single academic stroke center between January 2011 through December 2013. Multivariable logistic regression analyses were used to assess for factors independently associated with the presence of an abnormal MRV pelvis. Patients (47 ± 13 years...Continue Reading

Citations

Feb 27, 2016·Journal of cardiology·Fausto PizzinoConcetta Zito
Jun 24, 2016·Circulation Journal : Official Journal of the Japanese Circulation Society·Yee-Ping Sun, Shunichi Homma
Jun 18, 2015·Stroke; a Journal of Cerebral Circulation·Benjamin R MillerSophia Sundararajan
Oct 31, 2019·Arquivos de neuro-psiquiatria·Charles André
Jul 31, 2018·Case Reports in Cardiology·Dominika M ZoltowskaJagadeesh Kumar Kalavakunta
Sep 21, 2019·International Journal of Stroke : Official Journal of the International Stroke Society·Tomoyuki OharaAndrew M Demchuk
Jun 26, 2020·Frontiers in Neurology·Timo KahlesUNKNOWN International PFO Consortium NCT00859885

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