Abstract
The worldwide incidence of penicillin-resistant Streptococcus pneumoniae has increased at an alarming rate during the past decade. However, there has been little published data about the extent of this problem in Kuwait. The present study was undertaken to ascertain the preponderance of S. pneumoniae, either resistant or intermediate-resistant to penicillin, other beta-lactams and non-beta-lactam antimicrobials in Kuwait. Two hundred and fifty fresh isolates from as many patients suffering from different clinical conditions were collected from all clinics and hospitals in Kuwait. Optochin sensitivity and bile solubility tests reconfirmed these. Susceptibility testing to penicillin, ampicillin, cefuroxime, ceftriaxone, cefotaxime, imipenem, erythromycin, chloramphenicol, ciprofloxacin and vancomycin was done using E-test strips and to oxacillin, tetracycline, trimethoprim and amoxicillin-clavulanate by disc diffusion technique. Full and intermediate resistance to penicillin was observed in 1.6% and 52.8% of the isolates respectively. Full resistance to third-generation cephalosporins ranged from 0.4% to 3.2%, however, intermediate resistance to these antibiotics varied between 18.8% and 21.2%. Ampicillin resistance was noted in ...Continue Reading
References
Feb 1, 1992·The Journal of Antimicrobial Chemotherapy·A M Shibl, S S Hussein
Jul 1, 1992·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·M R Jacobs
Jul 1, 1992·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·P C Appelbaum
Dec 1, 1990·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·E Pérez-TralleroA Peris
Sep 24, 1982·JAMA : the Journal of the American Medical Association·M A MufsonD Hughey
May 1, 1995·Diagnostic Microbiology and Infectious Disease·C W StrattonM S Gelfand
Feb 1, 1995·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·V O RotimiP R Barbor
Sep 1, 1994·The Pediatric Infectious Disease Journal·R DaganK Klugman
Nov 1, 1994·Antimicrobial Agents and Chemotherapy·C P DoitE H Bingen
Jul 1, 1994·Infection·G E SchutzeR F Jacobs
Jan 1, 1994·The Pediatric Infectious Disease Journal·F Baquero, E Loza
Jun 15, 1996·BMJ : British Medical Journal·S K ObaroD C Henderson
Aug 1, 1996·The Journal of Antimicrobial Chemotherapy·M UwaydahZ Shihab
Oct 1, 1996·The Pediatric Infectious Disease Journal·P C Appelbaum
Sep 1, 1996·Diagnostic Microbiology and Infectious Disease·P C FuchsS D Brown
Jun 1, 1997·The Journal of Antimicrobial Chemotherapy·J George, I Morrissey
May 23, 1998·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·G D Campbell, R Silberman
Oct 10, 1998·Clinical Microbiology Reviews·S L Kaplan, E O Mason
Nov 3, 1998·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·G V DoernR N Jones
Sep 24, 1999·International Journal of Antimicrobial Agents·G F ArajS S Kanj
May 2, 2000·Journal of Chemotherapy·A M ShiblA O Osoba
Sep 1, 1995·International Journal of Antimicrobial Agents·M N ChowdhuryA M Kambal
Citations
Dec 19, 2012·Vaccine·Eiman Mokaddas, M John Albert
Aug 13, 2010·Journal of Infection and Public Health·Molly JohnyEdet E Udo
Jan 26, 2006·Journal of Chemotherapy·N Al SweihV O Rotimi
Dec 6, 2005·Journal of Chemotherapy·V O RotimiP Rajan
Dec 13, 2007·Journal of Chemotherapy·Z A MemishV O Rotimi
Jun 9, 2016·Expert Review of Vaccines·Eiman Mokaddas, M John Albert
Jun 23, 2016·Scientific Reports·Azza Aly ShaltoutM Alkhawari
Jan 11, 2008·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Eiman M MokaddasM John Albert
Jun 18, 2005·Medical Principles and Practice : International Journal of the Kuwait University, Health Science Centre·N BehbehaniT D Chugh
Dec 14, 2007·Clinical and Vaccine Immunology : CVI·Eiman M MokaddasM John Albert