Prevalence of positive microbiology results from donor cornea tissue in different methods of corneal transplantation

Cornea
Sumit GargRoger F Steinert

Abstract

To evaluate the prevalence of positive microbiology results (culture and/or Gram stain) in donor cornea tissue with newer transplant methods and to assess if the results subsequently correlate with higher incidence of clinical infection. A retrospective review of the microbiology records of 569 consecutive corneal transplants from July 2006 through July 2010 was performed to evaluate positive microbiology results in routine evaluation of cornea donor tissue. Microbiologic results were available for 544 of 569 transplants. The remaining 25 cases did not have specimens submitted for microbiologic analysis. In cases with results available, 46 (8.5%) positive reports occurred. In 10 of the 46 cases, Gram stain results were positive with subsequent negative cultures. Analysis revealed that the prevalence of positive results was 6 in 137 (4.4%), 14 in 127 (11.0%), and 26 in 271 (9.6%) for femtosecond laser-enabled keratoplasty, Descemet stripping automated endothelial keratoplasty, and conventional penetrating keratoplasty, respectively; 9 femtosecond deep anterior lamellar keratoplasty had no positive results. There was no significant relationship between the types of transplant procedures and the occurrence of positive microbiologi...Continue Reading

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Citations

May 20, 2014·Current Opinion in Ophthalmology·Grace E Boynton, Maria A Woodward
Dec 1, 2015·Current Ophthalmology Reports·Julie M Schallhorn, Jennifer Rose-Nussbaumer
Aug 2, 2017·The Open Ophthalmology Journal·Matthew Thompson, David Carli
Nov 21, 2020·Survey of Ophthalmology·Namrata SharmaAnthony Aldave
Oct 24, 2020·International Ophthalmology Clinics·Allister GibbonsNicolas A Yannuzzi

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