Prevalence of Proteinuria and Albuminuria in an Obese Population and Associated Risk Factors

Frontiers in Medicine
Jordan L RosenstockMichael F Michelis

Abstract

Obesity has been increasingly recognized as a risk factor for kidney disease and both proteinuria and microalbuminuria have been associated with obesity. The actual prevalence of microalbuminuria and proteinuria in obese patients in the United States (US) has not been clearly described in the literature. Furthermore, obesity is associated with risk factors of kidney disease, such as diabetes and hypertension (HTN), and the prevalence of proteinuria and albuminuria excluding these risk factors is uncertain. In this study, we collected urine albumin/creatinine and urine protein/creatinine ratios on obese patients undergoing bariatric surgery to determine the prevalence of albuminuria and proteinuria in obese patients with and without associated diabetes and HTN. The study included 218 obese patients undergoing bariatric surgery at a New York City hospital. The mean age was 42.1 ± 11.3 years. The mean body mass index (BMI) was 43.9 ± 8.1. Diabetes (DM) was present in 25%. HTN was present in 47%. The prevalence of proteinuria and albuminuria was 21% (95% CI: 15.8-27.1%) and 19.7% (95% CI: 14.2-26.2%) respectively. Among those without DM but who had HTN, 22.6% (95% CI: 12.9-35) had proteinuria and 17% (95% CI 8.4-30.9) had albuminur...Continue Reading

References

May 12, 2000·American Journal of Physiology. Renal Physiology·A ChagnacU Gafter
Mar 22, 2001·Kidney International·N KambhamV D D'Agati
Apr 1, 2003·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Sara-Joan Pinto-SietsmaUNKNOWN PREVEND Study Group
May 23, 2003·Journal of the American Society of Nephrology : JASN·Avry ChagnacYaacov Ori
Dec 8, 2006·Journal of the American Society of Nephrology : JASN·Ian H de BoerUNKNOWN Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study Research Group
Jan 25, 2008·Kidney International·A SerraA Ariza
Dec 1, 2009·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Farsad AfshinniaHassan N Ibrahim
May 6, 2011·International Urology and Nephrology·Rigas G Kalaitzidis, Kostas C Siamopoulos
Feb 10, 2016·Annals of Internal Medicine·Yoosoo ChangEliseo Guallar

❮ Previous
Next ❯

Citations

Sep 22, 2018·Obesity Surgery·Daniela S C MagalhãesDavide Carvalho
Aug 12, 2020·Nature Reviews. Nephrology·Neil G Docherty, Carel W le Roux

❮ Previous
Next ❯

Software Mentioned

SAS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Renal Nutrition : the Official Journal of the Council on Renal Nutrition of the National Kidney Foundation
Fabiola Martin-Del-CampoAlfonso M Cueto-Manzano
Nefrología : publicación oficial de la Sociedad Española Nefrologia
L Roberto Leon
Journal of Insurance Medicine
David N Duddleston
Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery
D P SchusterB J Needleman
© 2022 Meta ULC. All rights reserved