Prevalence of Psychiatric Diagnoses in Pediatric Chiari Malformation Type 1

Pediatric Neurosurgery
Maureen LacyDavid M Frim

Abstract

This cross-sectional study investigates the prevalence and risks for psychiatric diagnoses in a large cohort of children with Chiari malformation type 1 (CM1) presenting for neurosurgical evaluation. Children between the ages of 6 and 17 years who were evaluated and diagnosed with CM1 at a neurosurgery clinic were identified. Eighty-six participants were recruited for this study with an average age of 11 years. Parents of participants completed a pediatric medical history questionnaire and a semistructured interview regarding the child's psychiatric, developmental, medical, and family history. A review of medical records was completed to complement interview data. Elevated rates of psychiatric diagnoses, including attention deficit hyperactivity disorder (ADHD) (22.1%), anxiety (12.8%), and depression (10.5%), were identified in the study population when compared to published norms in the general population documented by the American Psychiatric Association in 2013. In addition, elevated rates of psychiatric diagnoses in first-degree relatives of study participants were also identified. A 2-step binary logistic regression analysis revealed that maternal complications during pregnancy (Wald = 6.52, p = 0.01) increased the risk o...Continue Reading

Citations

Jul 10, 2019·The Cerebellum·Maitane GarcíaJon Infante
Jun 19, 2019·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Luca MassimiM Caldarelli
Oct 9, 2020·Case Reports in Medicine·Anaïs DuBowSmadar Valérie Tourjman
Feb 21, 2021·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Seda Aybuke Sari, Unal Ozum
Sep 13, 2019·World Neurosurgery·Scott C SeamanBrian J Dlouhy
Mar 5, 2019·World Neurosurgery·Maureen LacyDavid M Frim

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