Prevalence of reticular pseudodrusen in eyes with newly presenting neovascular age-related macular degeneration

European Journal of Ophthalmology
C WildeW M K Amoaku

Abstract

To use multimodal imaging to evaluate the prevalence of reticular pseudodrusen (RPD) in eyes with newly presenting neovascular age-related macular degeneration (nAMD) in a UK population and explore associations with RPD and angiographic subtypes of nAMD. A retrospective review of all spectral-domain optical coherence tomography, color fundus photographs, red-free and blue channel images, and fundus fluorescein angiograms of 202 consecutive patients who presented to a rapid access macular clinic over a 4-year period was performed. All images were graded by at least 2 ophthalmologists for the presence of RPD and choroidal neovascular membrane (CNV) subtypes. A total of 231 consecutive eyes were studied, of which 131 (56.7%) were in women. Of these, 51 eyes with CNV (22.1%) had identifiable RPD, with one or more imaging methods in that eye. A total of 30.3% of patients with newly presenting CNV in either or both eyes had identifiable RPD. The RPD were bilateral in 85.4% of patients and were identified more commonly in women than men (72.5% vs 27.5%), a difference that reached statistical significance (p = 0.011). No association between RPD and any particular CNV subtype was demonstrated, including for retinal angiomatous prolifera...Continue Reading

References

Jul 1, 1991·Ophthalmology·R KleinL Hubbard
Sep 1, 1973·Archives of Ophthalmology·J D Gass
Jan 1, 1994·Eye·J P SarksM C Killingsworth
Feb 28, 2002·American Journal of Ophthalmology·Noemi LoisAlan C Bird
Apr 16, 2003·Archives of Ophthalmology·Redmer van LeeuwenPaulus T V M de Jong
Nov 16, 2005·Archives of Ophthalmology·Frederick L FerrisUNKNOWN Age-Related Eye Disease Study (AREDS) Research Group
Apr 12, 2006·Archives of Ophthalmology·Cristina A AugoodAstrid E Fletcher
Nov 24, 2006·Investigative Ophthalmology & Visual Science·R Theodore SmithN Victor Chong
Nov 6, 2007·Ophthalmology·Michael L KleinUNKNOWN AREDS Research Group
Nov 30, 2007·American Journal of Ophthalmology·Ronald KleinBarbara E K Klein
Oct 10, 2009·Ophthalmology·Sandrine A ZweifelYutaka Imamura
Nov 3, 2009·American Journal of Ophthalmology·R Theodore SmithGaetano Barile
Nov 27, 2010·The British Journal of Ophthalmology·John SarksMurray Killingsworth
Apr 19, 2011·Investigative Ophthalmology & Visual Science·Steffen Schmitz-ValckenbergUNKNOWN Geographic Atrophy Progression (GAP) Study Group
May 10, 2011·Ophthalmology·Nicole M PumariegaEric H Souied
Oct 15, 2011·American Journal of Ophthalmology·Mee Yon LeeDon-Il Ham
Nov 1, 2012·American Journal of Ophthalmology·Naoko Ueda-ArakawaNagahisa Yoshimura
Jun 21, 2014·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Ruth Esther Hogg

❮ Previous
Next ❯

Citations

Oct 10, 2018·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Antony J Wightman, Robyn H Guymer
Sep 27, 2020·BMC Ophthalmology·Daniel AhmedSiamak Ansari-Shahrezaei
Dec 23, 2020·Ophthalmology Retina·Shyamanga BorooahAndrew C Browning

❮ Previous
Next ❯

Methods Mentioned

BETA
RAP
RAPs

Software Mentioned

IMAGEnet iBase
IMAGEnet

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
Seigo YoneyamaHiroyuki Iijima
Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde
Raeba MathewSobha Sivaprasad
© 2021 Meta ULC. All rights reserved