Prevalence of Selenium, T-2 Toxin, and Deoxynivalenol in Kashin-Beck Disease Areas in Qinghai Province, Northwest China

Biological Trace Element Research
Ronghui LeiXiong Guo

Abstract

The aim of this study was to determine the levels of selenium, T-2 toxin, and deoxynivalenol (DON) contamination in Kashin-Beck disease (KBD) areas and provide information for understanding the high prevalence of KBD in Qinghai Province. A total of 183 subjects were chosen in a KBD-prevalent county (Guide County) and a non-KBD county (Huangzhong County) in Qinghai Province, northwestern China, and the samples of wheat flour, soil, drinking water and blood, urine, and hair of children were collected from these residents. The selenium concentrations from all these sources were determined using atomic fluorescence spectrophotometry. The levels of T-2 toxin and DON contamination in the wheat flour samples were assayed using HPLC-MS/MS. The average selenium content in the soil, drinking water, and wheat flour samples from KBD areas were 26.93 ± 10.06 μg/kg, 0.097 ± 0.038 μg/L, and 9.50 ± 7.17 μg/kg, respectively. Among these, the selenium levels in the drinking water and wheat flour samples from the KBD endemic county were significantly lower than those from the non-KBD county. For the selenium nutrient status, only the hair selenium concentration of children from the KBD endemic county was significantly lower than that from the non...Continue Reading

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Citations

Jan 29, 2017·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Xianglian LiuZonghui Yuan
Feb 15, 2019·Critical Reviews in Food Science and Nutrition·Sakshi MishraSrikanta Kumar Rath
May 6, 2019·Toxins·Jianbo QiuJianrong Shi
Jul 28, 2020·Environmental Geochemistry and Health·Marina Dos SantosFlavio Manoel Rodrigues da Silva Júnior
Jun 7, 2018·Hormones : International Journal of Endocrinology and Metabolism·Ana Valea, Carmen Emanuela Georgescu
Mar 21, 2018·Experimental and Therapeutic Medicine·Yujie NingXiong Guo
Oct 2, 2019·Archives of Toxicology·Chongshan DaiTony Velkov
Jan 29, 2021·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Xuliang ZhangYanfei Li
Apr 10, 2021·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Qirong LuXu Wang
May 23, 2020·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Yuxiao LiaoWei Yang
May 27, 2021·Analytical Methods : Advancing Methods and Applications·Ting GuoShuo Wang

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