Abstract
Cystic echinococcosis (CE) is one of the most widespread zoonotic helminthiases, which can last an asymptomatic infection for several years. The purpose of this study was to demonstrate serum antibody prevalence of CE among asymptomatic people in Uzbekistan using ELISA. A total of 2,547 serum samples were collected, 66 from confirmed CE patients and 2,481 of patients with other diseases than CE at a hospital in Tashkent, Uzbekistan. The serum samples were screened for CE specific IgG antibodies by ELISA using cystic fluid antigen obtained from sheep. The serum antibody positive rate was 89.4% (59/66) in CE and 3.6% (89/2,481) in other disease patients. The present ELISA recognized 89.4% sensitivity and 96.4% specificity. The ELISA absorbance of positive samples was distributed 0.271-0.971 for CE and 0.273-0.887 for other disease patients. The other disease patients with high absorbance over 0.3 were 50 (2.0%) who were presumed to be active CE patients. The patients in their 40s showed the highest positive rate of 5.2% (P=0.181), and women were 4.4% while men were 3.1% positive (P=0.136). The data confirmed that there are many asymptomatic patients of CE in Tashkent. It is indicated that CE is an endemic disease of public health...Continue Reading
References
Apr 25, 2003·Acta Tropica·Akira ItoPeter M Schantz
May 3, 2003·Research in Veterinary Science·P R Torgerson, C M Budke
Oct 25, 2003·Lancet·Donald P McManusPaul B Bartley
Aug 23, 2005·Emerging Infectious Diseases·Yu Rong YangDonald P McManus
Dec 20, 2005·Parasitology International·Paul R TorgersonBlok Shaikenov
May 19, 2006·FEMS Immunology and Medical Microbiology·Wenbao Zhang, Donald P McManus
Oct 22, 2008·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Pedro Moro, Peter M Schantz
Jan 30, 2009·Zoonoses and Public Health·B SarkariF Sedaghat
Nov 6, 2009·Interdisciplinary Perspectives on Infectious Diseases·Alessandra SiracusanoElena Ortona
Nov 28, 2009·Acta Tropica·Tiaoying LiPhilip S Craig
Oct 6, 2010·Acta Tropica·T G T NguyenP Dorny
Aug 10, 2011·Zoonoses and Public Health·M F HarandiP Deplazes
Jul 19, 2013·The Korean Journal of Parasitology·Yan JinSung-Tae Hong
Jul 19, 2013·The Korean Journal of Parasitology·Sung-Tae HongUtkir Otaboev
Aug 28, 2013·Acta Tropica·Ali Ahmet KilimcioğluUlgen Zeki Ok
Sep 13, 2014·Journal of Infection in Developing Countries·Serife AkalinAli Ihsan Bozkurt
Sep 12, 2015·The American Journal of Forensic Medicine and Pathology·Taner DaşHüsrev Demirel