PMID: 9005511Sep 1, 1996Paper

Prevalence of silent myocardial ischemia in non-insulin dependent diabetes

Revista de investigación clínica; organo del Hospital de Enfermedades de la Nutrición
H E Tamez-PérezM D Gómez-de-Ossio

Abstract

To evaluate the prevalence of silent myocardial ischemia in patients with non-insulin dependent diabetes mellitus with no symptoms of cardiac disease. Tertiary care center. 60 patients with non-insulin dependent diabetes mellitus; mean age 58 +/- 12 years, who had no symptoms of angina or any other clinical evidence of coronary artery disease and normal resting electrocardiogram. A control group of 57 healthy volunteers, matched for age and sex were included. All patients underwent a 24 hour electrocardiographic Holter monitoring test. An ischemic episode was defined as depression of the ST segment > or = 1 mm for > or = 1 min. 10 of the 60 diabetic (17%) were found to have silent myocardial ischemia and only 3/57 (5%) was detected in the controls. In a two years follow up, four diabetics developed symptomatic angina pectoris. Silent myocardial ischemia in asymptomatic diabetics occurs frequently; a lack of symptoms does not discard a myocardial ischemia, and the Holter recordings may help in its detection.

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