Prevalence of Subclinical Atherosclerosis and Risk of Atherosclerotic Cardiovascular Disease in Older Adults Living with HIV

AIDS Research and Human Retroviruses
Linda AurpibulPatou Masika Musumari

Abstract

Cardiovascular disease (CVD) is one among the leading causes of mortality in people living with HIV on antiretroviral treatment (ART) worldwide. We examined the prevalence of subclinical atherosclerosis, associated factors, and risk of CVD in older adults living with HIV (OALHIV). A cross-sectional study was conducted with patients aged ≥50 years with HIV infection receiving ART at community hospitals in Chiang Mai, Thailand. Age- and sex-matched patients without documented HIV infection who visited the general outpatient department were enrolled for comparison. Cardio-ankle vascular index (CAVI) and ankle-brachial index (ABI) were measured using the vascular screening system, VaSera System™ (Fukuda Denshi Co., Ltd., Japan) to determine subclinical atherosclerosis (defined as CAVI ≥9.0) and peripheral arterial disease (defined as ABI <0.9), respectively. The Ramathibodi-Electric Generating Authority of Thailand (RAMA-EGAT) scores to predict the risk of coronary stenosis and the 10-year risk of ASCVD by pooled cohort equation were calculated. One hundred fifty-five patients were enrolled (107 HIV/48 comparison). The mean age was 59.0 years (SD 6.1); 67 (43%) were male. Participants in the HIV and comparison group were similar wi...Continue Reading

References

Apr 13, 2010·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·UNKNOWN Antiretroviral Therapy Cohort Collaboration
Jan 14, 2011·European Heart Journal·Jason V Baker, Jens D Lundgren
Feb 2, 2013·Journal of the American College of Cardiology·Franck BoccaraAriel Cohen
Sep 11, 2016·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Angela M Thompson-PaulKate Buchacz
Mar 10, 2017·Pulse·Teerapat Yingchoncharoen, Piyamitr Sritara

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Software Mentioned

CAVI
EGAT
SPSS
RAMA
VaSera

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