Prevalence of traditional modifiable cardiovascular risk factors in patients with rheumatoid arthritis: comparison with control subjects from the multi-ethnic study of atherosclerosis.

Seminars in Arthritis and Rheumatism
Cecilia P ChungJoan M Bathon

Abstract

Despite the recognized risk of accelerated atherosclerosis in patients with rheumatoid arthritis (RA), little is known about cardiovascular risk management in contemporary cohorts of these patients. We tested the hypotheses that major modifiable cardiovascular risk factors were more frequent and rates of treatment, detection, and control were lower in patients with RA than in non-RA controls. The prevalence of hypertension, diabetes, elevated low-density lipoprotein (LDL) cholesterol, elevated body mass index, smoking, moderate-high 10-year cardiovascular risk and the rates of underdiagnosis, therapeutic treatment, and recommended management were compared in 197 RA patients and 274 frequency-matched control subjects, and their associations with clinical characteristics were examined. Eighty percent of RA patients and 81% of control subjects had at least 1 modifiable traditional cardiovascular risk factor. Hypertension was more prevalent in the RA group (57%) than in controls [42%, P = 0.001]. There were no statistically significant differences in the frequency of diabetes, elevated body mass index, smoking, intermediate-high 10-year coronary heart disease risk, or elevated LDL in patients with RA versus controls. Rates of newly...Continue Reading

References

May 1, 1984·British Journal of Rheumatology·P PriorC F Hawkins
Apr 1, 1994·Arthritis and Rheumatism·F WolfeM A Cathey
Mar 13, 1998·Annals of the Rheumatic Diseases·A SavolainenK Aho
May 21, 1998·The New England Journal of Medicine·D A RedelmeierG L Booth
May 21, 1998·The New England Journal of Medicine·R Steinbrook
Jan 14, 1999·The New England Journal of Medicine·R Ross
Jun 22, 1999·The New England Journal of Medicine·G D Sloop
Aug 17, 2000·JAMA : the Journal of the American Medical Association·C H MacLeanP G Shekelle
Jul 13, 2001·JAMA : the Journal of the American Medical Association·R B D'AgostinoUNKNOWN CHD Risk Prediction Group
Jul 10, 2003·JAMA : the Journal of the American Medical Association·Ihab Hajjar, Theodore A Kotchen
Oct 1, 1953·The New England Journal of Medicine·S COBBW BAUER
Jun 10, 2004·Arthritis and Rheumatism·Maarten BoersTheodore Pincus
Sep 11, 2004·Journal of the American College of Cardiology·Scott M GrundyUNKNOWN Coordinating Committee of the National Cholesterol Education Program
Mar 8, 2005·Arthritis and Rheumatism·Hilal Maradit-KremersSherine E Gabriel
May 10, 2008·Rheumatology·V F PanoulasG D Kitas
Jul 30, 2008·Diabetes Care·Richard KahnDavid Eddy
Nov 19, 2009·JAMA : the Journal of the American Medical Association·J Michael Gaziano, Thomas A Gaziano
Feb 2, 2010·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Rosario RossiMaria Grazia Modena
Feb 25, 2011·Annals of the Rheumatic Diseases·Cynthia S Crowson, Sherine E Gabriel

❮ Previous
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Citations

Mar 19, 2013·Rheumatology·Elizabeth J CoulsonHelen E Foster
Nov 26, 2013·Rheumatic Diseases Clinics of North America·Deepali SenRichard D Brasington
Nov 10, 2012·Rheumatic Diseases Clinics of North America·Ashima MakolEric L Matteson
May 9, 2014·Journal of Osteoporosis·Claudiu PopescuRuxandra Ionescu
Mar 25, 2016·Rheumatology·Deborah F van Breukelen-van der StoepManuel Castro Cabezas
Jul 15, 2015·Scandinavian Journal of Rheumatology·D F van Breukelen-van der StoepM Castro Cabezas
Jul 27, 2015·Current Rheumatology Reports·Catherine M McGrath, Stephen P Young
Sep 2, 2014·BioMed Research International·Jenny Amaya-AmayaAdriana Rojas-Villarraga
Apr 2, 2013·The Canadian Journal of Cardiology·Calin D Popa, Piet L C M van Riel
Oct 16, 2013·Atherosclerosis·D F van Breukelen-van der StoepM Castro Cabezas
May 18, 2016·International Journal of Cardiology·Sophie I MavrogeniJoao A C Lima
Oct 30, 2016·BMC Cardiovascular Disorders·Sophie MavrogeniGenovefa Kolovou
Apr 1, 2017·Current Rheumatology Reports·Ann M ChodaraChristie M Bartels
Apr 25, 2018·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Christie Michels BartelsMaureen Smith
Aug 2, 2013·Therapeutic Advances in Musculoskeletal Disease·Inge A M van den OeverMichael T Nurmohamed
May 26, 2012·Arteriosclerosis, Thrombosis, and Vascular Biology·Shuang ChenMoshe Arditi
Oct 17, 2016·The Journal of Rheumatology·Henning JansenUNKNOWN CARDIoGRAM Consortium
Mar 5, 2019·Heart Failure Reviews·Sophie I MavrogeniGenovefa Kolovou
Jul 18, 2012·Current Rheumatology Reports·Matxalen Amezaga Urruela, Maria E Suarez-Almazor
Jan 19, 2019·Zeitschrift für Rheumatologie·K Krüger, H Nüßlein
Jul 14, 2012·Current Rheumatology Reports·Christina Charles-Schoeman
Nov 30, 2019·Expert Review of Clinical Immunology·Santos CastañedaMiguel A González-Gay
Mar 8, 2013·Current Opinion in Rheumatology·Medha Barbhaiya, Daniel H Solomon
Jun 5, 2020·Nature Reviews. Rheumatology·Anne Grete SembSilvia Rollefstad

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