PMID: 6989972Jun 1, 1980Paper

Prevalence of type-specific group B streptococcal antibody in pregnant women

The Journal of Pediatrics
L C VogelS P Gotoff

Abstract

Immunoglobulin G antibody against the four major serotypes of group B streptococcus was measured by indirect immunofluorescence in the sera of 200 consecutive pregnant women seen in the obstetric screening clinic of an urban teaching hospital. Antibody was detectable in 26% of undiluted sera against serotype Ia, 52% against serotype Ib, 82% against serotype II, and 45% against serotype III. Only 9% had antibody against all four GBS types. When serotype-specific antibody prevalences in 108 women with GBS vaginal colonization were compared with prevalences in noncolonized women, only women colonized with GBS type Ia were more likely to have antibody against Ia than noncolonized women. Antibody prevalences in sera from 54 mothers whose infants developed invasive GBS disease were significantly lower than those in colonized or noncolonized women. Since low titers of IF antibody to GBS III were present in some sera from mothers of infected infants, the data were analyzed based on IF antibody titers associated with passive protection in a chick embryo model of GBS septicemia. None of the sera from mothers of infected infants had antibody levels associated with chick embryo protection. Less than 10% of women had titers associated with ...Continue Reading

References

Dec 1, 1976·The Journal of Clinical Investigation·V G HemmingH R Hill
Nov 1, 1977·The Journal of Infectious Diseases·P B Stewardson-KriegerS P Gotoff
Jan 1, 1978·Infection·P B Stewardson-Krieger, S P Gotoff
Feb 1, 1974·Journal of Medical Microbiology·R H George

❮ Previous
Next ❯

Citations

Sep 1, 1987·Indian Journal of Pediatrics·V Wahn
Sep 1, 1981·European Journal of Obstetrics, Gynecology, and Reproductive Biology·K K ChristensenP Christensen
Mar 12, 1981·The New England Journal of Medicine·J D Siegel, G H McCracken
Jun 17, 1997·Annals of the New York Academy of Sciences·M L Batrinos, C Panitsa-Faflia
Aug 1, 1985·American Journal of Obstetrics and Gynecology·A G SkidmoreA Smith
Jul 1, 1990·American Journal of Obstetrics and Gynecology·H M SilverH C Dillon
Jun 24, 2010·Clinics in Perinatology·Jennifer R Verani, Stephanie J Schrag
Apr 1, 1984·The Journal of Pediatrics·K M BoyerS P Gotoff
Apr 1, 1996·Pediatric Annals·B M Mercer, R G Briggs
Nov 18, 2016·Journal of Perinatology : Official Journal of the California Perinatal Association·V ParenteR G Greenberg
Jun 1, 1983·Current Problems in Pediatrics·K L CatesM Ballow

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.