PMID: 9180662Jun 1, 1997Paper

Prevalence of undiagnosed non-insulin-dependent diabetes mellitus and impaired glucose tolerance in a cohort of older persons with hypertension

Journal of the American Geriatrics Society
K C JohnsonR I Shorr

Abstract

To determine the prevalence of undiagnosed non-insulin-dependent diabetes mellitus (NIDDM) and impaired glucose tolerance (IGT) in a cohort of older persons with hypertension. To examine the usefulness of screening for NIDDM in this study population. Cross-sectional study. University of Tennessee, Memphis and the General Clinical Research Center (GCRC). Ninety-five participants in the Trial of Nonpharmacologic Interventions in the Elderly (TONE) study who agreed to participate in an ancillary study. A standard oral glucose tolerance test (OGTT) with insulin and C-peptide levels was performed before the beginning of the TONE intervention. In this cohort, 43 participants (45.3%) had normal glucose tolerance (NGT), 41 (43.2%) had IGT, and 11 (11.6%) had undiagnosed NIDDM. The positive predictive value for NIDDM of a fasting glucose > or = 115 mg/dL in our participants was 57%. Hyperinsulinemia occurred in only one participant, a subject in the IGT group. Our data demonstrate that undiagnosed NIDDM is common in our cohort of older persons who are being treated for essential hypertension and that impaired glucose tolerance may be more common than in the general population of the same age. Further, our data show that the vast majorit...Continue Reading

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Citations

Jun 26, 2002·Menopause : the Journal of the North American Menopause Society·Mithat ErenusKoray Elter
Oct 31, 2001·The American Journal of Geriatric Cardiology·R W Schrier
Jan 5, 2017·Nutrition Reviews·Omar Y Bello-ChavollaMauricio Hernández-Avila
Jul 18, 2002·Holistic Nursing Practice·R A Jones, R Stephens

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