PMID: 6990090Jan 1, 1980Paper

Prevalence, pathogenesis, and functional significance of aldosterone deficiency in hyperkalemic patients with chronic renal insufficiency

Kidney International
M SchambelanE G Biglieri

Abstract

Our findings indicate that hypoaldosteronism occurs commonly (23/31 patients) in hyperkalemic patients with chronic renal insufficiency and that the deficiency of aldosterone contributes to the pathogenesis of the hyperkalemia. In most patients (83%), hypoaldosteronism could be accounted for by deficient renal secretion of renin, but in some patients (17%) overt renin deficiency did not appear to be present, and therefore other (unidentified) causes of aldosterone deficiency must be invoked. The results also indicate that the urinary excretion rate of aldosterone secretion rate in this group of patients.

References

Sep 15, 1977·The New England Journal of Medicine·A SebastianR C Morris
Sep 1, 1975·Biochemical Medicine·M Sparagana
Sep 16, 1976·The New England Journal of Medicine·A deLeivaP G Zager
Feb 1, 1977·The Journal of Clinical Endocrinology and Metabolism·A RöslerS Ulick
Oct 1, 1977·The Journal of Clinical Endocrinology and Metabolism·G O PerezF H Katz
Oct 1, 1976·Diabetes·A R ChristliebJ A D'Elia
Apr 1, 1975·Annals of Internal Medicine·T Murray, M Goldberg
Jul 1, 1975·The Journal of Clinical Endocrinology and Metabolism·T HimathongkamG H Williams
Jun 3, 1972·Lancet·J R StockigtE G Biglieri
Jan 1, 1968·Nephron·A R GersteinT I Steinman
Feb 1, 1970·The American Journal of Medicine·J C McGiffT F Frawley
Aug 1, 1971·The Journal of Clinical Investigation·F BayardC J Migeon
May 1, 1972·Annals of Internal Medicine·G PerezG E Schreiner
Sep 21, 1972·The New England Journal of Medicine·M SchambelanE G Biglieri
May 1, 1973·The Journal of Clinical Endocrinology and Metabolism·P WeidmannS G Massry
Dec 1, 1974·Metabolism: Clinical and Experimental·M S OhE S Whang
Mar 1, 1966·The Journal of Clinical Investigation·M I NewR E Peterson
May 1, 1970·The Journal of Clinical Endocrinology and Metabolism·D MayesC A Nugent
Feb 1, 1969·The Journal of Clinical Endocrinology and Metabolism·A H Vagnucci
Jun 1, 1967·The Journal of Clinical Investigation·C FloodS Willoughby
Dec 1, 1959·Archives of Internal Medicine·S R HILLM C GAUTNEY
Aug 1, 1962·The Journal of Clinical Investigation·J R BLAIR-WESTM WINTOUR
May 1, 1963·The Journal of Clinical Investigation·J O DAVISJ T HIGGINS
Jul 1, 1964·The Journal of Clinical Endocrinology and Metabolism·S ULICKC U LOWE

❮ Previous
Next ❯

Citations

Oct 1, 1988·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·J Rodríguez-Soriano, A Vallo
Jun 8, 2010·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Jeffrey A Kraut, Nicolaos E Madias
Dec 25, 2010·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Anja Lehnhardt, Markus J Kemper
Apr 21, 2007·General Thoracic and Cardiovascular Surgery·Keiji KamoharaTsuyoshi Itoh
Jan 29, 2000·Kidney International·D Z LevineK D Burns
Jun 26, 2002·Kidney International·F John Gennari, Alan S Segal
Feb 12, 1981·The New England Journal of Medicine·R C Morris
Dec 29, 1983·The New England Journal of Medicine·F A WilliamsR M Carey
Apr 17, 1986·The New England Journal of Medicine·J L NadlerR Horton
Aug 1, 1988·Clinical and Experimental Pharmacology & Physiology·W R AdamA G Ellis
Feb 9, 2013·Clinical Journal of the American Society of Nephrology : CJASN·Nimrit GorayaDonald E Wesson
May 31, 2003·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Michelle S C KhooRichard Engleman
Aug 13, 2013·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Wei Chen, Matthew K Abramowitz
Jan 1, 1989·Contributions to Nephrology·S Garella
Oct 1, 1981·Kidney International·J J BourgoignieA Rabinovitch
Nov 1, 1985·Kidney International·S RastogiJ A Arruda
Jun 15, 2007·Kidney International·G GiebischC Wagner
Oct 1, 1990·Kidney International·N A Kurtzman
Jan 1, 1982·Kidney International·R J HenéE J Mees
Dec 1, 1983·Kidney International·N A Kurtzman
Dec 1, 1981·Kidney International·E McSherry
Apr 2, 2014·Steroids·Alejandro L ArreggerLiliana N Contreras
Nov 1, 1985·Clinics in Endocrinology and Metabolism·J C Melby
Mar 10, 1999·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·T KeilaniD Batlle
May 1, 1984·Disease-a-month : DM·D C Batlle, N A Kurtzman
May 1, 1987·The American Journal of Medicine·M F KalinB Zumoff
Jan 1, 1990·The Journal of Diabetic Complications·J UribarriH J Carroll
Sep 1, 1986·The Journal of Pediatrics·J Rodríguez-SorianoR Oliveros
Jun 11, 2002·Critical Care Clinics·F John Gennari
Jul 2, 2016·Kidney Research and Clinical Practice·Yuichiro UedaYoshiyuki Morishita
Jun 30, 2015·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Cory WilczynskiAlaleh Mazhari
Jan 9, 2015·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Giuseppe MulèSantina Cottone
Oct 1, 1991·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·M M SalemD C Batlle
Dec 4, 2014·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Aliaksandr BudovichBarbara Berger
Mar 2, 2018·Current Cardiology Reports·Jay Ian Lakkis, Matthew R Weir
Feb 6, 2009·Journal of the American Society of Nephrology : JASN·Fiona E Karet
Aug 17, 2018·Case Reports in Anesthesiology·Ahmed Abdelaal Ahmed MahmoudMargarita Blajeva
Aug 20, 2019·Physiological Research·J HajalN Fares
Mar 10, 1988·The New England Journal of Medicine·D C BatlleR Gupta
Jun 16, 2005·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Jeffrey A Kraut, Ira Kurtz
Aug 1, 1988·Kidney International·D G Warnock

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.