Prevalence, susceptibility profile and proteinase production of yeasts causing vulvovaginitis in Turkish women

APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica
Sema Keceli OzcanAyse Willke

Abstract

In this study the prevalence of vulvovaginal candidiasis (VVC), antifungal susceptibility and proteinase production of isolated Candida species were investigated. Vaginal swabs were collected from symptomatic women with vulvovaginitis attending the Obstetrics and Gynecology Clinic of Kocaeli University, Turkey. The relation between risk factors, such as pregnancy, diabetes mellitus, antibiotic and corticosteroid use, history of sexually transmitted diseases and contraceptive methods, was recorded. Candida spp. were identified by conventional methods, then evaluated for proteinase secretion in a medium containing casein. Antifungal susceptibility was determined according to the NCCLS microdilution method. The prevalence of women with vulvovaginitis was 35.7% (170/6080) and 16% (28/170) of them were diagnosed as VVC. Candida albicans was the dominant species: 21 (75%), followed by 4 C. glabrata (14%), 2 C. tropicalis (7%), and one C. krusei (3.5%). All isolates were susceptible to fluconazole, itraconazole and amphotericin B, except one C. krusei, one C. glabrata and one C. albicans that were resistant to fluconazole. Proteinase production was determined in 19 (90.5%) C. albicans and in all C. tropicalis isolates. Proteinase acti...Continue Reading

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Citations

Dec 23, 2015·Critical Reviews in Microbiology·Bruna GonçalvesSónia Silva
Jan 1, 2014·Journal of Clinical Laboratory Analysis·Atta Yazdanpanah, Tzar Mohd Nizam Khaithir
Feb 23, 2007·Journal of Dental Research·L LiA Dongari-Bagtzoglou
Nov 6, 2018·Journal of Fungi·Olufunmilola MakanjuolaSamuel A Fayemiwo
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Nov 16, 2018·Indian Journal of Medical Microbiology·Krishnapriya KalaiarasanLatha Chaturvedula
Mar 7, 2017·Research in Microbiology·Mathieu CauchieKatrien Lagrou

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