Preventing Continuous Positive Airway Pressure Failure: Evidence-Based and Physiologically Sound Practices from Delivery Room to the Neonatal Intensive Care Unit

Clinics in Perinatology
Clyde J WrightRichard A Polin

Abstract

Routine use of continuous positive airway pressure (CPAP) to support preterm infants with respiratory distress is an evidenced-based strategy to decrease incidence of bronchopulmonary dysplasia. However, rates of CPAP failure remain unacceptably high in very premature neonates, who are at high risk for developing bronchopulmonary dysplasia. Using the GRADE framework to assess the quality of available evidence, this article reviews strategies aimed at decreasing CPAP failure, starting with delivery room interventions and followed through to system-based efforts in the neonatal intensive care unit. Despite best efforts, some very premature neonates fail CPAP. Also reviewed are predictors of CPAP failure in this vulnerable population.

Citations

May 21, 2020·Journal of Perinatology : Official Journal of the California Perinatal Association·Carl H BackesCharles V Smith
May 16, 2019·Journal of Perinatology : Official Journal of the California Perinatal Association·Venkatakrishna KakkilayaVishal S Kapadia
Jul 2, 2019·NeoReviews·Walid A Hussain, Jeremy D Marks
Oct 6, 2020·International Journal of Pediatrics·Walufu Ivan Egesa, William Mugowa Waibi
Jan 25, 2021·Journal of Paediatrics and Child Health·Anna Madeline KidmanRisha Bhatia
Dec 19, 2020·Pulmonary Pharmacology & Therapeutics·Beena G SoodXinguang Chen
Mar 18, 2021·Acta Paediatrica·Benjamin W Ackermann, Kirsten Glaser
Aug 21, 2020·Seminars in Perinatology·Ganga KrishnamurthyAnna Penn
Sep 30, 2020·Brazilian Journal of Physical Therapy·Bruna S P P VieiraVerônica F Parreira
Sep 24, 2021·Pediatrics·Venkatakrishna B KakkilayaMambarambath A Jaleel
Dec 9, 2021·Paediatric Anaesthesia·Sven M Schulzke, Benjamin Stoecklin

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