Preventing depression and anxiety in young people: a review of the joint efficacy of universal, selective and indicated prevention

Psychological Medicine
E A StockingsG Patton

Abstract

Depression and anxiety (internalizing disorders) are the largest contributors to the non-fatal health burden among young people. This is the first meta-analysis to examine the joint efficacy of universal, selective, and indicated preventive interventions upon both depression and anxiety among children and adolescents (5-18 years) while accounting for their co-morbidity. We conducted a systematic review of reviews in Medline, PsycINFO and the Cochrane Library of Systematic Reviews, from 1980 to August 2014. Multivariate meta-analysis examined the efficacy of preventive interventions on depression and anxiety outcomes separately, and the joint efficacy on both disorders combined. Meta-regressions examined heterogeneity of effect according to a range of study variables. Outcomes were relative risks (RR) for disorder, and standardized mean differences (Cohen's d) for symptoms. One hundred and forty-six randomized controlled trials (46 072 participants) evaluated universal (children with no identified risk, n = 54) selective (population subgroups of children who have an increased risk of developing internalizing disorders due to shared risk factors, n = 45) and indicated prevention (children with minimal but detectable symptoms of a...Continue Reading

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Citations

May 14, 2016·Lancet·George C PattonRussell M Viner
Oct 5, 2016·Depression and Anxiety·Judy GarberV Robin Weersing
Nov 9, 2016·Clinical Psychology Review·Aliza Werner-SeidlerHelen Christensen
Mar 7, 2018·The Australian and New Zealand Journal of Psychiatry·Anthony F Jorm, Roger T Mulder
Sep 28, 2017·The Journal of School Nursing : the Official Publication of the National Association of School Nurses·Latefa Ali DardasLeigh Ann Simmons
Jun 30, 2018·Journal of the International AIDS Society·Allison K GrovesDhayendre Moodley
Oct 31, 2018·The Journal of Psychology·Maite GaraigordobilElena Bernarás
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Aug 28, 2020·Frontiers in Psychology·Ian Andrew PlattJerome Carson
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Mar 17, 2018·Social Psychiatry and Psychiatric Epidemiology·Tamar Mendelson, William W Eaton

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