Preventing Heart Failure in Inflammatory and Immune Disorders

Current Cardiovascular Risk Reports
Maya Serhal, Chris T Longenecker

Abstract

Patients with chronic inflammatory diseases are at increased risk for heart failure due to ischemic heart disease and other causes including heart failure with preserved ejection fraction. Using rheumatoid arthritis and treated HIV infection as two prototypical examples, we review the epidemiology and potential therapies to prevent heart failure in these populations. Particular focus is given to anti-inflammatory therapies including statins and biologic disease modifying drugs. There is also limited evidence for lifestyle changes and blockade of the renin-angiotensin-aldosterone system. We conclude by proposing how a strategy for heart failure prevention, such as the model tested in the Screening To Prevent Heart Failure (STOP-HF) trial, may be adapted to chronic inflammatory disease.

References

Jul 26, 1990·The New England Journal of Medicine·B LevineM Packer
Jun 16, 1984·Lancet·M F MartinV Wright
Jul 23, 2003·AIDS·Peter F Currie, Nicholas A Boon
Jul 22, 2004·JAMA : the Journal of the American Medical Association·Véronique L RogerSteven J Jacobsen
Nov 18, 2004·Annals of the Rheumatic Diseases·S Van DoornumI P Wicks
Jan 7, 2005·The New England Journal of Medicine·Steven Grinspoon, Andrew Carr
Feb 1, 2005·Journal of the American College of Cardiology·Frank HermannFrank Ruschitzka
Feb 5, 2005·Arthritis and Rheumatism·Paulo J NicolaSherine E Gabriel
Apr 27, 2007·The New England Journal of Medicine·UNKNOWN DAD Study GroupJens D Lundgren
May 26, 2010·Annals of the Rheumatic Diseases·Kimberly P LiangSherine E Gabriel
Oct 5, 2010·Seminars in Arthritis and Rheumatism·Alper M van SijlMichael T Nurmohamed
May 17, 2011·The Journal of Rheumatology·Elena MyasoedovaSherine E Gabriel
Aug 6, 2011·Antiviral Therapy·Jacopo VecchietRaffaele De Caterina
Aug 23, 2011·The American Journal of Cardiology·Renata MichaDariush Mozaffarian
Sep 20, 2011·Rheumatology·Aamer SandooGeorge D Kitas
Feb 22, 2012·Translational Research : the Journal of Laboratory and Clinical Medicine·Chris T Longenecker, Brian D Hoit
May 18, 2012·The Journal of Infectious Diseases·Priscilla Y HsuePeter W Hunt
May 15, 2012·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Felicia C ChowVirginia A Triant
Jun 19, 2012·International Journal of Cardiology·Salvatore CorraoGiuseppe Licata
Jul 24, 2012·JAMA : the Journal of the American Medical Association·Sharath SubramanianSteven K Grinspoon
Aug 2, 2012·Therapeutic Advances in Musculoskeletal Disease·Jonathan L Marks, Christopher J Edwards
Oct 10, 2012·Arthritis and Rheumatism·Mary Chester M WaskoMichael M Ward
Nov 17, 2012·Annals of the Rheumatic Diseases·Daniel H SolomonJ R Curtis

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Related Feeds

Anti-inflammatory Treatments

A drug or substance that reduces inflammation (redness, swelling, and pain) in the body. Anti-inflammatory agents block certain substances in the body that cause inflammation and swelling. Discover the latest research on anti-inflammatory treatments here