PMID: 11916458Mar 28, 2002Paper

Preventing infection from reusable medical equipment: a systematic review

BMC Infectious Diseases
Will SopwithPaul Garner

Abstract

In 2000, the World Health Organization (WHO) had eight sets of conflicting recommendations for decontaminating medical equipment. We conducted a systematic review of observational studies to assist WHO in reconciling the various guidelines. This paper summarises the methods developed and illustrates the results for three procedures--alcohol, bleach and povidone iodine. We developed a Medline search strategy and applied inclusion criteria specifying the decontamination procedures of interest and an outcome of microbial destruction for a set of marker organisms. We developed protocols to assess the quality of studies and categorised them according to the reliability of the methods used. Through an iterative process we identified best practice for the decontamination methods and key additional factors required to ensure their effectiveness. We identified 88 published papers for inclusion, describing 135 separate studies of decontamination. For disinfection with alcohol, best practice was identified from 23 studies as an exposure to 70-80% ethanol or isopropanol for at least 5 minutes. Bleach was effective for sterilization at a concentration of 5000 ppm for 5 minutes and for disinfection at 1000 ppm for 10 minutes (33 studies). Po...Continue Reading

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Citations

Sep 13, 2011·Human Reproduction·Lodovico Parmegiani, Laura Rienzi
Jul 17, 2008·Journal of Medical Microbiology·Karen Smith, Iain S Hunter
Aug 14, 2012·The Laryngoscope·Rodrigo C SilvaPatrick J Antonelli
Jan 1, 2012·Biosensors·Malcolm J FarrowPatricia Connolly
Jun 25, 2008·Antimicrobial Agents and Chemotherapy·Jeniel E NettDavid R Andes

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