Prevention and Management of Thromboembolism in Pregnancy When Heparins Are Not an Option

Clinical Obstetrics and Gynecology
Andra H James

Abstract

Heparins, unfractionated heparin, and low molecular weight heparin, are the preferred anticoagulants in pregnancy. There are circumstances, however, in which an alternative to heparin should be considered. These circumstances include, the presence of heparin resistance, a heparin allergy manifesting as heparin-induced skin reactions or heparin-induced thrombocytopenia, and the presence of a mechanical heart valve. From time to time, the obstetrician is called on to make recommendations about anticoagulants in pregnancy, including in circumstances in which an alternative to heparin has been suggested or is necessary. In this article, these circumstances are reviewed and alternative anticoagulants are discussed.

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Citations

May 5, 2021·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Carl-Erik DempfleAndreas Heinken
Aug 19, 2021·European Heart Journal·Gabriele Egidy AssenzaJolien Roos-Hesselink

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