Prevention of alopecia in medical and interventional chemotherapy patients

Journal of Cutaneous Medicine and Surgery
Adam A DmytriwPeter J Green

Abstract

Chemotherapy-induced alopecia is one of the most distressing side effects of cancer treatment. Although there have been a number of investigated strategies to reduce this, there is no standard of care for treatment. This review aims to summarize the relevant evidence for the treatments available for chemotherapy-induced alopecia. A literature search using PubMed and the MEDLINE subengine was completed. The terms "chemotherapy," "alopecia," "quality of life," and "strategies" were used, and articles from the last 10 years were considered. The pediatric population was not investigated. Physical therapies for alopecia prevention have shown some promise but range from insufficient to detrimental depending on the type of cancer. Cold caps may be more effective than tourniquets and may be associated with fewer metastatic events. Pharmacologic therapies, both immunomodulators and growth factors, have stood the test of several trials to date. In particular, cyclosporine has been shown either to prevent alopecia or promote hair growth during a chemotherapy regimen. Although the evidence is not yet overwhelming, it is becoming clear that a combination of mechanical and chemical interventions may help compensate for the downfalls of eithe...Continue Reading

References

Jan 1, 1992·Scandinavian Journal of Caring Sciences·A J TierneyS J Closs
Feb 1, 1992·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·J J JimenezA A Yunis
Mar 1, 1985·Acta Radiologica. Oncology·L Vendelbo Johansen
Jan 1, 1995·Dermatology : International Journal for Clinical and Investigative Dermatology·A M HusseinW P Peters
May 1, 1993·Southern Medical Journal·A M Hussein
Mar 1, 1997·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·I G RonS Chaitchik
Mar 1, 1997·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·K MünstedtH Vahrson
May 17, 2000·The Australasian Journal of Dermatology·D TranC W Chow
Feb 7, 2002·European Journal of Cancer Care·D Batchelor
Jul 16, 2003·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Jörg EickerMark Berneburg
Aug 6, 2003·Acta Oncologica·Svein DuelandKjell Magne Tveit
Apr 29, 2006·The Journal of Investigative Dermatology·Sascha JungJürgen Lademann
Jun 24, 2006·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Tobias W FischerAndrzej Slominski
Sep 15, 2006·Pharmaceutical Research·Jie WangJessie L-S Au
Jun 26, 2007·Dermatology : International Journal for Clinical and Investigative Dermatology·Ralph M Trüeb
Mar 19, 2008·Cell Stress & Chaperones·Joaquin J JimenezRichard Voellmy
Apr 4, 2009·Seminars in Cutaneous Medicine and Surgery·Ralph M Trüeb
Sep 14, 2011·Dermatologic Therapy·Caroline E Yeager, Elise A Olsen
Jun 2, 2012·Seminars in Interventional Radiology·Michael NaumannRamona Gupta

❮ Previous
Next ❯

Citations

Apr 5, 2016·Biological & Pharmaceutical Bulletin·Seeun ParkYoung-Hee Lim
Jun 20, 2017·The British Journal of Dermatology·C DessiniotiA J Stratigos
May 28, 2016·British Journal of Nursing : BJN·Annie Young, Azra Arif
Apr 6, 2018·Journal of Maxillofacial and Oral Surgery·Manal KhanAnuj Jain
Sep 25, 2015·World Journal of Gastroenterology : WJG·Tao ChenWei Hu
Jan 4, 2019·American Journal of Clinical Dermatology·Jenna R StoehrStefan Vanderweil

❮ Previous
Next ❯

Software Mentioned

MEDLINE

Related Concepts

Related Feeds

Acute viral rhinopharyngitis

Acute viral rhinopharyngitis, also known as "common cold", is an acute, self-limiting viral infection of the upper respiratory tract involving the nose, sinuses, pharynx and larynx. Discover the latest research on acute viral rhinopharyngitis here.