Prevention of catheter-related infections: the skin

Nutrition
R Darouiche, I Raad

Abstract

Although intravascular devices have become indispensable tools in the care of seriously ill patients, the morbidity and mortality resulting from catheter-related infections and the high cost of managing such complications may offset the benefits derived from these devices. A scientific understanding of the pathogenesis, microbiology, and risk factors involved in catheter-related infection is the cornerstone of any effective preventive approach. Prevention of vascular catheter-related infection mostly centers around inhibiting the adherence to the catheter of microorganisms originating from either the skin or the catheter hub. Two general approaches can be used nonexclusively for successful prevention of vascular catheter-related infection. The first approach does not use antimicrobial agents and includes measures such as placement and maintenance of vascular catheters by a skilled infusion therapy team and use of maximal sterile barriers. The second approach uses antimicrobial agents and involves the application of topical disinfectants such as chlorhexidine, use of silver-impregnated subcutaneous cuffs (for short-term central venous catheters), flushing catheters with a combination of antimicrobial and antithrombotic agents, a...Continue Reading

References

Aug 1, 1992·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·I I Raad, G P Bodey
Oct 8, 1992·The New England Journal of Medicine·D K CobbB M Farr
May 8, 1991·JAMA : the Journal of the American Medical Association·G D KamalP J Jebson
Mar 1, 1986·JPEN. Journal of Parenteral and Enteral Nutrition·D B NelsonS D Davis
Apr 1, 1994·Artificial Organs·R BambauerP Sioshansi
May 25, 1994·JAMA : the Journal of the American Medical Association·D PittetR P Wenzel
Apr 1, 1994·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·I I RaadG P Bodey
Feb 1, 1996·The Journal of Infectious Diseases·I RaadG P Bodey
Feb 1, 1996·The Journal of Infectious Diseases·I RaadG P Bodey
Nov 1, 1995·Antimicrobial Agents and Chemotherapy·I RaadG P Bodey

❮ Previous
Next ❯

Citations

Feb 9, 2010·Annals of Biomedical Engineering·Antonio Peramo, Cynthia L Marcelo
Mar 23, 2010·Pharmaceutical Research·Anubhav Arora, Samir Mitragotri
Jan 21, 2000·Journal of Controlled Release : Official Journal of the Controlled Release Society·I A RojasD W Grainger
Jun 13, 1998·International Journal of Antimicrobial Agents·R O DarouicheM D Mansouri
Apr 20, 2004·Current Opinion in Clinical Nutrition and Metabolic Care·Simon P Allison, Dileep N Lobo
Jan 25, 2003·Journal of Infusion Nursing : the Official Publication of the Infusion Nurses Society·Lynn C Hadaway
Nov 2, 2001·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·J Carratalà
Aug 5, 2004·American Journal of Infection Control·Matthias TrautmannPhilipp M Lepper
Jul 1, 2006·Polymer Bulletin·Robert C Schmeltzer, Kathryn E Uhrich
Mar 23, 2004·Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia·Jirí GalloVlasta Tichá
Apr 15, 2000·Annals of Internal Medicine·R J SherertzE F Haponik
Oct 28, 2019·British Journal of Nursing : BJN·Steve HillFiona Martin
Apr 16, 2004·Journal of Infusion Nursing : the Official Publication of the Infusion Nurses Society·Girolamo A OrtolanoBarry Wenz

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.