Jan 1, 1977

Prevention of complications of histamine liberation occurring after administration of anesthetic agents and adjuvants

Annales de l'anesthésiologie française
M C LaxenaireJ Barlier

Abstract

To protect the organism against histamine liberated during anesthesia specific premedication is used including:--hydroxyzine (Atarax) which blocks the H1 histamine receptors, and is an anxiolytic,--tritoqualine (Hypostamine) which inhibits histamine synthesis,--epsilon aminocaproic acid (Hemocaprol) which prevents the antigen-antibody reaction and blocks the alternate route of complement. Twenty five patients were thus premedicated, 25 others received no premedication. All were put to sleep with Alfatesine. The results were judged on the clinical symptoms and the variations of histamine in whole blood. This premedication seems very efficacious, in particular in subjects with a high risk of histamine liberation.

  • References
  • Citations

References

  • We're still populating references for this paper, please check back later.
  • References
  • Citations

Citations

  • This paper may not have been cited yet.

Mentioned in this Paper

Immediate Hypersensitivity
Adjuvants, Anesthesia
Anaphylaxis
General Anesthesia
Epsikapron
Preanesthetic Medication
Histamine Release
Ceplene
Hydroxyzine Dihydrochloride
Histamine Antagonists

About this Paper

Related Feeds

Atopic Dermatitis

Atopic dermatitis is a chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. Discover the latest research on atopic dermatitis here.

Anaphylaxis

Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death.

Related Papers

RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
H J ReimannM Reiser
Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research
J SeifertH J Egbers
The International Journal of Risk & Safety in Medicine
P SoyerP Rouleau
© 2020 Meta ULC. All rights reserved