Prevention of contrast induced nephropathy by ischemic preconditioning in patients undergoing percutaneous coronary angiography

The Egyptian Heart Journal : (EHJ) : Official Bulletin of the Egyptian Society of Cardiology
Ahmed Shawky ElserafyTamim Hegazy

Abstract

Contrast-induced nephropathy (CIN) is the acute deterioration of renal function after parenteral administration of radio contrast media in the absence of other causes. The true incidence of CIN varies because of differences among the published studies in the definition of CIN, the proportion of high-risk patients, the types of contrast media, and the use of preventive measures. Remote ischemic preconditioning (IPC) may offer a non-pharmacological prevention strategy for lowering CIN in patients undergoing coronary procedures. The assumption that IPC produces protective effects on tissues or organs by multiple brief cycles of ischemia and reperfusion applied to another remote tissue or organ. To investigate the effect of ischemic preconditioning in prevention of CIN in patients with renal impairment undergoing percutaneous coronary angiography. In this study, 100 patients undergoing elective PCI with a base line creatinine clearance <60 ml/min were studied. Patients were divided into two equal groups (ischemic preconditioning group and control group). The incidence of CIN was markedly lower in ischemic preconditioning group 14% VS 38% in control group. The incidence of CIN difference as was found to be (24%). Amount of dye used,...Continue Reading

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Feb 1, 2013·Clinical Kidney Journal·José António Lopes, Sofia Jorge

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Citations

Jan 9, 2020·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Raymond PranataBambang B Siswanto

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Methods Mentioned

BETA
percutaneous coronary angiography

Software Mentioned

SPSS
PRO

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