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Prevention of delayed vasospasm by an endothelin ETA receptor antagonist, BQ-123: change of ETA receptor mRNA expression in a canine subarachnoid hemorrhage model

Journal of Neurosurgery

Nov 1, 1994

Seigo ItohYoshiyuki Kuchino

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Abstract

The authors investigated the roles of endothelin (ET)-1 and the ETA receptor in the pathogenesis of delayed cerebral vasospasm following subarachnoid hemorrhage (SAH). A study was made of the preventive effect of a novel ETA receptor antagonist, BQ-123, on vasospasm and the expression o...read more

Mentioned in this Paper

Vascular Constriction (Function)
Subarachnoid Hemorrhage
Endothelin A Receptor Antagonists
Cyclo(D-Trp-D-Asp-Pro-D-Val-Leu)
BQ 123
Endothelin Receptor
Body Surface Area Formula for Dogs
Canis familiaris
Dog family
MRNA Expression
Paper Details
References
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  • Citations43
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Prevention of delayed vasospasm by an endothelin ETA receptor antagonist, BQ-123: change of ETA receptor mRNA expression in a canine subarachnoid hemorrhage model

Journal of Neurosurgery

Nov 1, 1994

Seigo ItohYoshiyuki Kuchino

PMID: 7931624

DOI: 10.3171/jns.1994.81.5.0759

Abstract

The authors investigated the roles of endothelin (ET)-1 and the ETA receptor in the pathogenesis of delayed cerebral vasospasm following subarachnoid hemorrhage (SAH). A study was made of the preventive effect of a novel ETA receptor antagonist, BQ-123, on vasospasm and the expression o...read more

Mentioned in this Paper

Vascular Constriction (Function)
Subarachnoid Hemorrhage
Endothelin A Receptor Antagonists
Cyclo(D-Trp-D-Asp-Pro-D-Val-Leu)
BQ 123

Related Papers

Paper Details
References
  • References40
  • Citations43
1234
  • References40
  • Citations43
12345

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