Prevention of Esophageal Stricture After Endoscopic Submucosal Dissection: A Systematic Review

World Journal of Surgery
Jiang-Ping YuWang Shi

Abstract

Endoscopic submucosal dissection (ESD) is rapidly becoming a favored method for removing early esophageal cancer, but the residual defects can be complicated with strictures that require repeated endoscopic balloon dilatation. Measures for preventing the post-ESD strictures have been sought. We conducted a systematic review of recent studies to evaluate these methods. We searched MEDLINE, Cochrane Central Register of Controlled Trials, Embase, and Google Scholar until November 30, 2014. Included studies were prospective and retrospective one- and two-arm studies. All studies had to include at least on preventive method for post-ESD stricture. Thirteen studies were included in the review. Among the studies that used corticosteroids to prevent post-ESD stricture, we found that (1) injection of triamcinolone acetonide into the esophageal lesion resulted in a substantial reduction in the rate of stricture, and (2) the use of oral prednisolone was associated with a significantly reduced rate of dilatation sessions and stricture. Studies of other preventative measures included more recently developed scaffold-based and cell-based tissue-engineering approaches which seem very promising but require additional rigorously controlled stud...Continue Reading

References

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Aug 24, 2007·Digestive Diseases and Sciences·Yasuharu SaitoYoshihide Fujiyama
Mar 24, 2009·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·H MizutaS Onishi
Sep 24, 2010·Journal of Clinical Gastroenterology·Yasumasa EzoeTsutomu Chiba
Jun 26, 2012·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Takeshi YamashinaHiroyasu Iishi
Dec 20, 2012·Experimental and Therapeutic Medicine·Changxiong WangPing Chen
Feb 2, 2013·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Hajime IsomotoKazuhiko Nakao
Nov 26, 2013·The Annals of Thoracic Surgery·Alejandro NieponiceAdolfo E Badaloni
Nov 12, 2014·World Journal of Gastroenterology : WJG·Shinichiro KobayashiTeruo Okano

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Citations

Sep 17, 2016·Gastrointestinal Endoscopy·Horst Neuhaus
Mar 6, 2019·Esophagus : Official Journal of the Japan Esophageal Society·Keitaro TakahashiToshikatsu Okumura

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