Prevention of iron deficiency by milk fortification. The Chilean experience

Acta Paediatrica Scandinavica. Supplement
Manuel OlivaresA Stekel

Abstract

A large proportion of the milk consumed by infants in Chile is distributed by a National Food Supplementary Program. Efforts to prevent iron deficiency by milk fortification started several years ago. Initially a field study involving the simple addition of ferrous sulfate to a low-fat powdered milk was only partially successful due to the relatively low iron absorption from this product. Following the observation that the enrichment of milk with ascorbic acid markedly improved iron bioavailability, a new fortified formula was developed and has been tested in the field since 1976. This is powdered full-fat milk, biologically acidified and fortified with 15 mg Fe, as ferrous sulfate, and 100 mg ascorbic acid per 100 g powder. In a pilot study, 276 infants spontaneously weaned before 3 months of age received the fortified milk, and 278 infants receiving unfortified milk served as controls. At the end of the study (15 months of age) anemia (Hb less than 11 g/dl) was present in 25.7% of unfortified infants compared with only 2.5% in those fortified. Saturation of Transferrin less than 9% was present in 33.8% and serum ferritin less than 10 micrograms/l in 39.1% of the nonfortified infants. The figures for the fortified group were 7...Continue Reading

References

Aug 1, 1978·The Journal of Pediatrics·U M Saarinen
Feb 1, 1988·The American Journal of Clinical Nutrition·A StekelF Pizarro
Jun 1, 1986·The American Journal of Clinical Nutrition·A StekelM Amar
Feb 1, 1987·The American Journal of Clinical Nutrition·F PizarroA Stekel
Jan 1, 1966·American Journal of Diseases of Children·M B Andelman, B R Sered

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Citations

Dec 1, 2000·Nutrition Research Reviews·R J Moy
May 7, 2010·The American Journal of Clinical Nutrition·Richard D SembaKlaus Kraemer
Jul 8, 2008·Journal of Industrial Microbiology & Biotechnology·Emilina SimovaZhelyazko Simov
Mar 5, 2019·Food and Nutrition Bulletin·Manuel Ruz, Noel W Solomons
Mar 1, 1997·The Proceedings of the Nutrition Society·B A Wharton
Sep 1, 1994·Acta Paediatrica. Supplement·B A WhartonP H Scott
Nov 12, 2011·Food and Nutrition Bulletin·Daphna K Dror, Lindsay H Allen
Jun 1, 1994·Cadernos de saúde pública·M A Cardoso, M de V Penteado
Sep 2, 2003·The Journal of Nutrition·Sean R Lynch, Rebecca J Stoltzfus
Mar 2, 2002·Early Human Development·R M Angulo-KinzlerB Lozoff

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