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Prevention of myocardial Ca overload and necrotization by Mg and K salts or acidosis

Recent Advances in Studies on Cardiac Structure and Metabolism

Jan 1, 1975

J JankeH Sigel

PMID: 743

Abstract

The crucial point in the pathogenesis of isoproterenol-induced myocardial necrotization is an abundant intracellular Ca accumulation leading to high energy phosphate exhaustion. Accordingly, in the early stage of the isoproterenol-induced necrotization process, the onset of ATP and crea...read more

Mentioned in this Paper

Neoton
Pathogenic Aspects
Necrosis
Pathogenesis
Phosphocreatine
Calcium
Protoplasm
Potassium
Uptake
Myocardium
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Prevention of myocardial Ca overload and necrotization by Mg and K salts or acidosis

Recent Advances in Studies on Cardiac Structure and Metabolism

Jan 1, 1975

J JankeH Sigel

PMID: 743

DOI:

Abstract

The crucial point in the pathogenesis of isoproterenol-induced myocardial necrotization is an abundant intracellular Ca accumulation leading to high energy phosphate exhaustion. Accordingly, in the early stage of the isoproterenol-induced necrotization process, the onset of ATP and crea...read more

Mentioned in this Paper

Neoton
Pathogenic Aspects
Necrosis
Pathogenesis
Phosphocreatine
Calcium
Protoplasm
Potassium
Uptake
Myocardium

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