Prevention of myopia progression with 0.05% atropine solution

Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics
Jong-Jer LeePei-Chang Wu

Abstract

The aim of this study was to evaluate the efficacy of 0.05% atropine solution for controlling myopia progression in school-aged children. This retrospective, case-control study enrolled myopic school-aged children who had presented at Kaohsiung Chang Gung Memorial Hospital (Kaohsiung, Taiwan) from 2001 to 2004. A group of 57 children (30 boys, 27 girls; 6-12 years of age) with regular follow-up was divided into a subgroup of 21 children (12 boys, 9 girls) who received atropine eyedrops (0.05%) every evening, and a subgroup of 36 children (18 boys, 18 girls), who remained untreated, served as controls. The changes in refractive status of 114 eyes in 57 children were collected and compared for patients treated with 0.05% atropine eyedrop and those without medical control. The initial spherical equivalent of refractive status range was between -0.5 and -5.5 D. Mean myopia progression for the group of patients treated with 0.05% atropine eyedrop (n = 21) was -0.28 +/- 0.26 D/year, significantly lower than that of the control group of -0.75 +/- 0.35 D/year (36 patients; P < 0.001). The 0.05% atropine group had a significant lower ratio of uncontrolled myopia, that progressed greater than -0.50 D in 1 year, relative to the controls (...Continue Reading

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Citations

Aug 12, 2010·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Po-Chiung FangPei-Chang Wu
Jun 9, 2011·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Yan-yan SongHong-zhuan Chen
Aug 6, 2011·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Pei-Chang WuPo-Chiung Fang
Dec 21, 2013·Eye·T A Aller
Dec 10, 2013·American Journal of Ophthalmology·Audrey ChiaDonald Tan
Aug 1, 2015·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·Shu YiXiao-Li Zeng
Mar 28, 2012·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Hong-Ming ChengChing-Ying Cheng
Jun 8, 2014·Complementary Therapies in Medicine·Han-Chih Cheng, Yi-Ting Hsieh
Jan 22, 2014·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Shi-Ming LiMichel Millodot
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Mar 1, 2019·Investigative Ophthalmology & Visual Science·Christine F WildsoetJames S Wolffsohn
Nov 7, 2019·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·António QueirósJosé González-Méijome
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Nov 23, 2011·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Tzu-En J WuHarn-Shen Chen
Oct 1, 2013·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Jeffrey CooperFrederick M Wang
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Apr 8, 2020·Clinical Ophthalmology·Sangeethabalasri PugazhendhiAllan A Hunter
Oct 30, 2015·Eye & Contact Lens·Jeffrey J Walline
Jan 1, 2021·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Wen-Yi WangI-Jong Wang
Jun 9, 2020·Journal of Optometry·Negareh YazdaniJavad Heravian Shandiz
Jan 27, 2021·Journal of the Chinese Medical Association : JCMA·Yih-Shiuan KuoPei-Yu Lin

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